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Pain, Hem, Onco 2
BDK
Generic | Brand | Pharmacologic Category | Common Indication | Essential knowledge |
---|---|---|---|---|
Methotrexate (PO) | Trexall | Anti-metabolite (Folic Acid antagonist) | Rheumatoid arthritis, Crohn's Disease, Psoriasis, various hematologic and solid tumors | Key Side Effects: stomatitis, diarrhea, nausea, vomiting, thrombocytopenia, leukopenia, increased hepatic transaminases, pulmonary fibrosis (rare) US Boxed Warnings: serious toxic reactions (only use in life-threatening neoplastic disease, severe psorias |
Anastrazole (PO) | Arimidex | Aromatase inhibitor | Hormone receptor-positive breast cancer | Key Side Effects: fatigue, rash, flushing, hot flashes, arthralgia, nausea, vomiting, hypertension, peripheral edema, osteoporosis Other Notes: cardiovascular side effects (i.e., hypercholesterolemia, CAD); fetal toxicity (CI in pregnancy) |
Phentermine (PO) | Adipex-P | CNS Stimulant | Obesity | Key Side Effects: hypertension, nausea, dizziness, xerostomia, primary pulmonary hypertension (rare) Other Notes: only approved for short-term use; CI in those with a history of cardiovascular disease or drug abuse, pregnancy, hyperthyroidism, or within |
Ferrous sulfate (PO) | FeroSul, SlowFe | Iron supplement | Iron deficiency anemia | Boxed Warning: Accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old Key Side Effects: nausea, stomach upset, constipation (dose-related), dark and tarry stools |
Cyanocobalamin (Vitamin B12) (PO, IM, SL, intranasal) | ----- | Water -soluble vitamin | Vitamin B12 deficiency (manifests as macrocytic anemia) | No major side effects |
Folic Acid (PO) | ---- | Water soluble vitamin | Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy | No major side effects |