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Endocrine 2

GenericBrandPharmacologic CategoryCommon IndicationsEssential Knowledge
drospirenone and ethinyl estradiol (PO) Yasmin, Yaz Contraceptive Contraception, acne Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease
levonorgestrel and ethinyl estradiol (PO) Lutera, Levora, Seasonique Contraceptive Contraception, acne Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease
norethindrone and ethinyl estradiol (PO) Junel, Loestrin, Microgestin Contraceptive Contraception, acne Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease
norethindrone, ethinyl estradiol, and ferrous fumarate (PO) Lo Loestrin Fe, Microgestin Fe Contraceptive Contraception, acne Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease
norgestimate and ethinyl estradiol (PO) Ortho Tri-Cyclen Lo, Tri-Sprintec, Sprintec Contraceptive Contraception, acne Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease
norgestrel and ethinyl estradiol (PO) Crysell-28, Low-Ogestrel Contraceptive Contraception, acne Key Side Effects: nausea, changes in menstrual flow, breast tenderness, thromboembolic disorders, headache US Boxed Warnings: increased risk of cardiovascular events in women >35 years old who smoke Other Notes: CI in hepatic dysfunction, thromboembolic disorders, breast cancer, and cardiovascular disease
estrogens, conjugated (equine) (PO, topical) Premarin Estrogen derivative Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause KSE: irritation at application site (trans. patch only), abdominal pain, breast tenderness, thromboembolic disorders (MI, stroke, VTE) USBW: increased risk of breast cancer; should not be used for dementia prevention; increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; should not be used for prevention of cardiovascular disease ON: CI in hepatic dysfunction, thromboembolic disorders, cardiovascular disease, breast cancer, and estrogen-dependent tumor
estradiol (transdermal, PO) Transdermal: Vivelle Dot, PO: Estrace Estrogen derivative Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause KSE: irritation at application site (trans. patch only), abdominal pain, breast tenderness, thromboembolic disorders (MI, stroke, VTE) USBW: increased risk of breast cancer; should not be used for dementia prevention; increased risk of endometrial cancer if not used concomitantly with progestin in women with a uterus; should not be used for prevention of cardiovascular disease ON: CI in hepatic dysfunction, thromboembolic disorders, cardiovascular disease, breast cancer, and estrogen-dependent tumor
medroxyprogesterone (PO) Provera Progestin Abnormal uterine bleeding, secondary amenorrhea Key Side Effects: acne, abnormal menstrual bleeding, headache, amenorrhea US Boxed Warnings: increased risk of breast cancer; should not be used for dementia prevention; should not be used for prevention of cardiovascular disease Other Notes: CI in thromboembolic disorders, cardiovascular disease, estrogen or progesterone-dependent tumors, undiagnosed abnormal genital bleeding, hepatic impairment
Created by: Xander635
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