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Endocrine 3

GenericBrandPharmacologic CategoryCommon IndicationsEssential Knoweldge
testosterone gel (topical) AndroGel, Fortesta, Vogelxo Androgen Hypogonadism Key Side Effects: contact dermatitis, acne, increased prostate specific antigen (PSA), emotional lability, hypertension US Boxed Warnings: secondary exposure may result in virilization (especially in children); CI in males with breast or prostate cancer and pregnant women
alendronate (PO) Fosamax Bisphosphonate Osteoporosis Key Side Effects: dyspepsia, gastroesophageal reflux disease, hypocalcemia, atypical fractures, osteonecrosis of the jaw Other Notes: CI in patients with abnormalities of the esophagus; administer ≥30 minutes before food or drink (except plain water); remain upright for 30 minutes following dose to reduce esophageal irritation
ibandronate (PO, IV) Boniva Bisphosphonate Osteoporosis Key Side Effects: dyspepsia, gastroesophageal reflux disease, hypocalcemia, atypical fractures, osteonecrosis of the jaw Other Notes (oral only): CI in patients with abnormalities of the esophagus; administer ≥60 minutes before food or drink (except plain water); remain upright for 60 minutes following dose to reduce esophageal irritation
raloxifene (PO) Evista Selective estrogen receptor modulator (SERM) Osteoporosis, breast cancer prevention Key Side Effects: hot flashes, leg cramps, peripheral edema, arthralgia US Boxed Warnings: increased risk of thromboembolism; increased risk of death caused by stroke in patients with cardiovascular disease
sildenafil (PO) Viagra, Revatio Phosphodiesterase-5 enzyme (PDE5) inhibitor ED, PAH Key Side Effects: priapism, headache, flushing, visual disturbance Other Notes: CI with concomitant use of nitrates (may cause severe hypotension)
tadalafil (PO) Cialis Phosphodiesterase-5 enzyme (PDE5) inhibitor ED, BPH Key Side Effects: priapism, headache, flushing, visual disturbance Other Notes: CI with concomitant use of nitrates (may cause severe hypotension)
Created by: Xander635
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