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Neuro/Psych 5

GenericBrandPharmacologic CategoryCommon IndicationsEssential Knowledge
buspirone (PO) Buspar Antianxiety agent Anxiety Key Side Effects: dizziness, drowsiness, nausea
alprazolam (PO) Xanax Benzodiazepine Anxiety Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours
clonazepam (PO) Klonopin Benzodiazepine Anxiety, seizure disorders Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours
diazepam (PO, IV) Valium Benzodiazepine Anxiety, seizure disorders, acute alcohol withdrawal Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours
lorazepam (PO, IV) Ativan Benzodiazepine Anxiety, seizure disorders, acute alcohol withdrawal Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours
midazolam (IV, IM) Versed Benzodiazepine Anesthesia, sedation Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours
temazepam (PO) Restoril Benzodiazepine Anxiety, insomnia Key Side Effects: daytime sedation, performance impairment, tolerance, dependence, anterograde amnesia, withdrawal US Boxed Warning: risk of profound sedation, respiratory depression, coma and death with opioids; risk of abuse, misuse, and addiction; risk of dependence and withdrawal reactions Other Notes (lorazepam IV only): parenteral formulation contains propylene glycol and may be associated with toxicity if used ≥ 48 hours
eszopiclone (PO) Lunesta Hypnotic Insomnia Key Side Effects: decreased ability to function the next morning, somnolence, headache, dizziness, xerostomia, dysgeusia US Boxed Warning: serious injuries, including death, have occurred because of complex sleep behaviors (i.e., sleepwalking, sleep driving, and engaging in other activities while not fully awake); contraindicated in patients with history of complex sleep behaviors
zolpidem (PO) PO: Ambien, Ambien CR SL: Intermezzo Hypnotic Insomnia Key Side Effects: decreased ability to function the next morning, somnolence, headache, dizziness, xerostomia, anterograde amnesia US Boxed Warning: serious injuries, including death, have occurred because of complex sleep behaviors (i.e., sleepwalking, sleep driving, and engaging in other activities while not fully awake); contraindicated in patients with history of complex sleep behaviors
propofol (IV) Diprivan Sedative, anticonvulsant Sedation for mechanical ventilation, procedural anesthesia, status epilepticus Key Side Effects: hypotension, hypertriglyceridemia, propofol- related infusion syndrome (rare)
dexmedetomidine (IV) Precedex Alpha2 agonist, sedative Sedation for mechanical ventilation or procedures Key Side Effects: bradycardia, hypotension
Created by: Xander635
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