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What are 3 conditions that affect medications?
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What kinds of medications are affected by liver disease?
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Ch.13

Drug-to-Disease Interactions

TermDefinition
What are 3 conditions that affect medications? -Kidney disease -Heart failure -Liver disease
What kinds of medications are affected by liver disease? Medications with high volumes of distribution that bind to plasma proteins
What kinds of medications are affected by kidney disease/ Medications with low volumes of distribution and low plasma protein binding
Which measure of kidney function is the basis of many dosing regimens in patients with kidney disease? Creatine Clearance
Which liver enzymes are used to test liver function in when determining dosage regimens? -ALT -AST -Alkaline phosphatase -Albumin -Total protien
What is heart failure? The inability of the heart to pump blood ineffectively
What is a common result of heart failure? Edema (Pooling of fluid around the ankles)
What are the effects of oral corticosteroids in patients with heart failure? Increased sodium and water retention leading to fluid overload AND edema
What happens if people that have had heart failure take metformin? Increased risk of lactic acidosis
What happens to patients that have had heart failure when they take CCB's? Decreased cardiac conduction
Created by: almestica.nashia
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