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BRCA1
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48 cancer gene panel

Gene and what types of cancer the gene mutation can cause

QuestionAnswer
BRCA1 Breast, Ovarian, Pancreatic, Prostate Cancer
BRCA2 Breast, Ovarian, Skin, Pancreatic, Prostate Cancer
MLH1, MSH2, MSH6, PMS2, EPCAM Ovarian, Colorectal, Uterine, Skin, Pancreatic, Gastric, Prostate, Other Cancers
APC Colorectal, Gastric, Endocrine, Other Cancers
MUTYH (Biallelic) Colorectal, Other Cancers
MUTYH (Monoallelic) none
CDKN2A(p16INK4a), CDKN2A (p14ARF) Skin, Pancreatic Cancer
CDK4 Skin, Pancreatic Cancer
TP53 Breast, Colorectal, Uterine, Skin, Pancreatic, Gastric, Prostate, Renal, Other Cancers
PTEN Breast, Colorectal, Uterine, Skin, Renal, Endocrine, Other Cancers
STK11 Breast, Ovarian, Colorectal, Uterine, Pancreatic, Gastric, Lung, Other Cancers
CDH1 Breast, Gastric Cancer
BMPR1A, SMAD4 Colorectal, Gastric, Other Cancers
PALB2 Breast, Ovarian, Pancreatic Cancer
CHEK2, CHEK2 (biallelic) Breast, Colorectal Cancer
ATM Breast, Pancreatic, Prostate Cancer
BARD1 Breast Cancer
BRIP1 Ovarian Cancer
RAD51C, RAD51D Breast, Ovarian Cancer
POLD1, POLE, GREM1, AXIN2 Colorectal Cancer
HOXB13 Prostate Cancer
NTHL1 (BIALLELIC) Breast, Colorectal, Uterine, Other Cancers
NTHL1 (MONOALLELIC) none
MSH3 (BIALLELIC) Colorectal Cancer
MSH3 (MONOALLELIC) none
FH Skin, Renal, Other Cancers
FLCN Skin, Renal, Other Cancers
MET Renal Cancer
TSC1/TSC2 Renal, Other Cancers
SDHA, SDHB, SDHC, SDHD Renal, Endocrine, Other Cancers
VHL Renal, Endocrine, Other Cancers
BAP1 Skin, Renal, Other Cancers
MITF Skin Cancer
TERT Skin, Other Cancers
CTNNA1 Gastric Cancer
EGFR Lung Cancer
MEN1 Endocrine, Other Cancers
RET Endocrine, Other Cancers
Created by: borend2023
Popular Genetics sets

 

 



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