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Autonomic III b
Muscarinic Receptor Antagonists
Question | Answer |
---|---|
What are the 4 main muscarinic receptor antagonists? | atropine, Scopolamine, Ipratropium, Benztropine/Trihexyphenidyl |
What is the use of Atropine? | antispasmadic (M3), antisecretory (M1 and M3), AchE overdose management, antidiarrheal (M1), ophthamology (M3), and prevent vagal rxn |
What is the use of Scopolamine? | motion sickness, sedation, memory block (CNS) |
What is the use of Ipratropium? | Asthma, COPD --> NO CNS and NO change in mucus |
What is the use of Benztropine and Trihexyphenidyl? | CNS entry via lipid soluble; for Parkinsonism and antipsychotic sx remedy |