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Exam 1 Drugs
NYU
Question | Answer |
---|---|
Chlorpromazine (Thorazine) | - aliphatic phenothiazine, antipsychotic - used to treat schizophrenia, control mani type of manic depressive illness, psychosis, and for preoperative sedation and N/V |
Fluphenazine (Prolixin) | - antipsychotic, neuroleptic, piperazine phenothiazine - used to manage symptoms of psychosis, including schizophrenia, and to manage N/V and intractable hiccups |
Thioridazine (Mellaril) | - piperdine phenothiazine, antipsychotic - tx for schizophrenia, psychosis if unresponsive to other meds |
Quetiapine fumarate (Seroquel) | - dibenzothiazepine, atypical antipsychotic - tx for schizophrenia, bipolar disorder |
Tranylcypromine sulfate (Parnate) | - antidepressant, MAOIs - tx for depression |
Amitriptyline (Elavil) | - tricyclic antidepressant - tx for depression, bipolar, depression with organic disease, alcoholism, migraine, anxiety |
Fluoxetine (Prozac) | - antidepressant, selective serotonin reuptake inhibitor (SSIR) - tx for depression, bipolar, depression with organic disease, alcoholism, migraine, urinary incontinence |
Buproprion (Wellbutrin) | - atypical antidepressant - tx for depression, smoking cessation |
Benztropine (Cogentin) | - antiparkinson agent, anticholinergics - treat acute dystonia that occurs with antipsychotics |
Haldoperidol (Haldol) | - nonphenothiazine, antipsychotics - tx for schizophrenia, manic states, drug-induced psychosis |
Risperidone (Risperdal) | - atypical antipsychotic, nonphenothiazine - tx of schizophrenia, bipolar disorder, mood stabilizer, manage symptoms of psychosis |
Ziprasidone (Geodon) | - atypical antipsychotic - tx of schizophrenia, bipolar, mood stabilizer |
Lorazepam (Ativan) | - benzodiazepine, anticonvulsants, sedative hypnotics, anxiolytics - tx of anxiety, pre-op sedative, control alcohol syndrome |
Diazepam (Valium) | - antianxiety, anticonvulsants, sedative-hypnotics, skeletal muscle relaxants, benzodiazepine - tx of anxiety, pre-op sedative, status epilepticus, symptoms of alcohol withdrawal |
Phenytoin (Dilantin) | - antiepileptic - used to control and prevent seizures |
Lithium | - antidepressant, mood stabilizer - used to treat manic phase, bipolar, and decrease sodium level - therapeutic drug range 0.5 - 1.5 mEq/L |
Digoxin (Lanoxin) | - cardiac glycoside - used to treat HF, atrial tachycardia, flutter or fibrillation - therapeutic drug range 0.5 - 2.0 ng/mL |
Diphenhydramine (Benadryl) | - antihistamine, antitussive - tx of allergic rhinitis and itching, prevention of motion sickness, sleep aid |
Ephedrine (Efedron) | - systemic decongestant, bronchodilator, alpha adrenergic agonist - relief of allergic rhinitis, nasal congestion, sinusitis and asthma, improves narcotic impaired respiration, treat hypotension |
Phenylephrine (Neo-Synephrine, Sinex) | - vasopressor, alpha adrenergic agonist, decongestant - treat rhinitis, less potent than ephedrine |
Pseudoephedrine (Novafed, Sudafed) | - nasal decongestant, alpha adrenergic agonist - treat rhinitis, nasal congestion |
Fluticasone (Flonase) | - intranasal glucocorticoids, anti-inflammatory steroids - treatment of seasonal allergic rhinitis |
Dextromethorphan hydrobromide (Robitussin DM) | - antitussives - temperature suppression of a nonproductive cough; decrease viscosity of tenacious secretions |
Guaifenesin (Robitussin, Anti-Tuss, Glycotuss) | - expectorant - treatment of dry, unproductive cough |
Epinephrine (Adrenalin) | - nonselective alpha, beta1 & 2 agonist, bronchodilator - relief of acute brochoconstriction and to combate anaphylactic reaction, increase blood pressure, increase airway patency, emergency restoration of circulaton |
Isoproterenol (Isuprel) | - nonselective beta 1 and 2 agonist, bronchodilator - treat bronchospasm, asthma; promote bronchodilation |
Albuterol (Proventil, Ventolin) | - selective beta adrenergic, bronchodilator - treatment of asthma, bronchitis and exercise induced bronchospasm and other COPD, "rescue inhaler" |
Theophylline (Theo-Dur, Slo-bid) | - bronchodilator, methylxanthines - to promote bronchodilation and treat asthma and COPD, relazes smooth muscle |
Aminophylline (Somophyllin) | - theophylline preparation, methylxantines, bronchodilator - IV for acute asthmatic attacks |
Caffeine | - bronchodilator, methylxanthines - treatment of asthma |
Ipratropium bromide (Atrovent) | - anticholinergic, bronchodilator - treat bronchospasm associated with COPD, asthma |
Montelukast sodium (Singulair) | - bronchodilator, leukotrine receptor antagonist - for prevention and treatment of asthma |
Beclomethasone (Vanceril) | - glucocorticoids, anti-inflammatory - decrease frequency and severity of asthma attacks |
Advair Diskus | - steroid (fluticasone) + LA beta 2 agonist (salmeterol) - managing asthma, alleviate airway constriction and inflammation |
Cromolyn (Intal) | - antiasthmatics, mast cell stabilizers - prophylactic treatment of bronchial asthma, inhibits release of histamine to prevent asthma reaction |
Nedocromil sodium (Tilade) | - anti-inflammatory, antiasthmatics - manage mild-severe asthma, prevent bronchospasm and acute asthma attack |
Acetylcysteine (Mucomyst) | - mucolytic - decrease viscosity of mucous -> liquefy and loosen thick mucous secretions |
Dexamethasone (Decadron) | - anti-inflammatory, glucocorticoids (steroid) - systemi anti-inflammatory effect |
Naloxon (Narcan) | - opioid antagonist - reverse opioid depression, ex. respiratory depression |
Nitroglycerin (Nitrostat, Nitro-Bid, Transderm-Nitro) | - antianginal, nitrates - to control angina pectoris, decrease myocardial oxygen demand, decrease preload and afterload, dilate coronary arteries and promotes vasodilation |
Atenelol (Tenormin) | - beta adrenergic blocker, antianginals, antihypertensives - treatment angina pectoris, hypertension, prevent myocardial infarction |
Propanolol (Inderal) | - nonselective beta blocker, antianginal, antihypertensive, antidysrhythmia - used to be used for prevention of angina but not now because risk of bronchospasm, used for hypertension and arrhythmia |
Metoprolol (Lopressor) | - selective beta blocker, antianginal, antihypertensive - decrease cardiac oxygen demand, decrease heart rate and contractility, decrease hypertension, cardiac output, system vascular resistant and renin release, prevent MI, manage stable, symptomatic HF |
Verapamil (Calan) | - antianginal, Ca+ channel blocker, antidysrhythmia, antihypertensive - long term tx of variant and stable angina, cardiac dysrhythmia and hypertension, decrease cardiac oxygen demand, contractility and workload |
Nifedipine (Procardia) | - antianginal, Ca+ channel blocker, antihypertensive - long germ tx of angina, vasospactic angina, potent Ca+ blocker, promotes vasodilation of coronary arteries and peripheral vessels, hypertension |
Diltiazem (Cardizem) | - antianginal, Ca+ channel blocker, antidysrhythmias, antihypertensives - tx of hypertension, long term tx of angina pectoris, Prinzmetal's angina, cardiac dysrhythmias |
Amlodipine (Norvac) | - antihypertensive, Ca+ channel blockers, antianginal, antidysrhythmias - tx of mild to moderate hypertension, angina pectoris & Prinzmetal's, promote vasodilation |
Furosemide (Lasix) | - loop diuretic - treat fluid retention/overload caused by HF, renal dysfunction, cirrhosis, hypertension, acute pulmonary edema |
Hydrochlorothiazide (HydroDIURIL, HCT2, Esidrix, Oretic) | - thiazide diuretic, antihypertensive - mild-moderate tx of hypertension, tx of edema associated with CHF, renal dysfunction, cirrhosis and increase urine output |
Methyldopa (Aldomet) | - centrally acting alpha agonist, antihypertensive - tx of stage 1 - 3 hypertension, long acting, decrease PVR and increase vasodilation |
Prazosin HCL (Minipress) | - antihypertensive: alpha adrenergic blocker - control of hypertension, refractory HF and treat benign prostatic hypertrophy |
Captopril (Capoten) | - ACE inhibitor, antihypertensive - manage hypertension, HF, treat diabetic neuropathy in type 1 DM |
Losartan potssium (Cozaar) | - antihypertensive, Angiotensin II Receptor Blocker - manage hypertension, prevent stroke in hypertension patient |
Atorvastatin (Lipitor) | - antilipidemic, HMG-CoA reductase inhibitor - decrease cholesterol levels and serum lipids, esp. LDL and triglyceride, primary prevention of coronary heart disease in asymptomatic pt with high total and LDL cholesterol and decrease HDL |
Procainamide (Pronestyle, Procan SR) | - Class I: fast (sodium) channel blockers IA, antidysrhythmias - atrial and ventricular dysrhythmias, PAT, supra vent. dysrhythmias, PVCs, v tach, decrease automaticity, conduction velocity, increase refractory period |
Lidocaine (Xylocaine) | - Class I, IB, antidysrhythmic - treat and prevent acute ventricular dysrhythmias following MI and cardiac surgery |
Propafenone (Rythmol) | - Class I, IC, antidysrhythmic - tx of life threatening ventricular dysrhythmias |
Acebutolol (Sectral) | Class II, beta blocker, cardioselective beta adrenergic antagonist, antidysrhytmic, antihypertensive - aid in treatment of recurrent stable ventricular dysrhythmias, angina pectoris and hypertension |
Amiodarone (Cordarone) | - Class III, potassium channel blockers, antidysrhythmic - tx of life threatening ventricular dysrhythmia, a fib, prolongs repolarization |
Heparin (Lipo-Hepin) | - anticoagulant, antithrombotics - tx against clotting, thromboembolic disorders, inhibits thrombin and prevent fibrinogen to fibrin |
Warfarin (Coumadin) | - only oral anticoagulant - prevent blood clotting, depress hepatic synthesis of vitamin K clotting factors |
Argatroban (Acova) | - anticoagulant, thrombin inhibitor - directly inhibits thrombin and decrease development of new thrombosis, treatment of thrombosis |
Bivalinrudin (Angiomax) | - anticoagulant, thrombin inhibitor - binds with and inhibit free flowing thrombin, prevent clot formation in patients with unstable angina undergoing cardiac angioplasty |
Lepirudin (Refludan) | - anticoagulant, thrombin inhibitors - prophylaxis and treatment of thrombosis because of HIT (heparin induced thrombocytioemia) |
Desirudin (Iprivask) | - anticoagulant, thrombin inhibitor - subcutaneous direct thrombin inhibitor, prevent DVT after hip replacement |
Aspirin | - antiplatlet - prevent thrombosis before or after transient ischemic attacks, CVA or MI |
Dipyridamole (Persantine) | - antiplatelet, coronary vasodilator, platelet adhesion inhibitor, ADP antagonist - prevent thromboembolism post MI and associated with prosthetic devices (heart valves) and prevent TIA |
ticlopidine (Ticlid) | - antiplatelet, platelet aggregation inhibitor - prevent stroke and thrombin formation, treatment of intermittent claudication and sickle cell |
Clopidogrel (Plavix) | - antiplatelet, platelet aggregation inhibitor - prevent recurrence of MI, stroke and prevent vascular death |
Cilostazol (Pletal) | - antiplatelet - inhibits plateley aggregation, vasodilator, treatment of intermittent claudication |
Streptokinase (Streptase) | - thrombolytic, plasmogen activators - dissolves blood clots cause by coronary artery thrombi, DVT, PE |
Alteplase (tPA) | - thrombolytic - dissolve clot following an acute MI, PE, acute ischemic stroke |
Urokinase (Abbokinase) | - thrombolytic - dissolve clots following PE, acute MI, acute ischemic stroke |