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Gastrointestinal Pharmacology

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Antacid Agents Action are used to chemically neutralize gastric acid and increase the intragastric pH.
Primary antacids are classified as aluminum-containing, calcium carbonate-containing, magnesium-containing or sodium bicarbonate-containing.
Antacid Agents Indications: ) episodic minor gastric indigestion or heartburn, peptic ulcer, gastroesophageal reflux disease (GERD
Antacid Agents Side effects: acid rebound phenomenon, constipation or diarrhea (depending on the antacid), may effect metabolism of other medications, electrolyte imbalances
Antacid Agents Implications for PT: Since these agents are well tolerated there are typically no side effects that interfere with physical therapy.
Patients are more likely to participate in therapy with effective management of gastrointestinal issues using these agents.
Antacid Agents Aluminum-containing: Antacid Agents Basaljel (aluminum carbonate gel);
Antacid Agents Calcium carbonate containing: Tums (calcium carbonate);
Antacid Agents Magnesium-containing: Milk of Magnesia (magnesium hydroxide);
Antacid Agents Sodium bicarbonate-containing: Antacid Agents Bromo seltzer (sodium bicarbonate)
Proton Pump Inhibitor Agents Action: inhibit the H+/K+ -ATPase enzyme that blocks secretion of acid from gastric cells into the stomach.
Proton pump inhibitor agents agents prevent erosive esophagitis in patients with GERD and acid secretion dysfunction.
Proton pump inhibitor agents . may also possess antibacterial effects against helicobacter pylori (H. pylori) infection
Proton Pump Inhibitor Agents Indications: gastric and duodenal ulcers, GERD, H. pylori
Proton Pump Inhibitor Agents Side effects: increased susceptibility to gastrointestinal infections, headache, diarrhea, abdominal pain,
Proton Pump Inhibitor Agents Side effects gastric polyps, acid rebound with discontinuation of agent
Proton Pump Inhibitor Agents Implications for PT: Since these agents are well tolerated there are typically no side effects that interfere with physical therapy.
Proton Pump Inhibitor Agents Implications for PT Patients are more likely to participate in therapy with effective management of gastrointestinal issues using these agents.
Created by: micah10
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