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Class 4 Alcohol/Psyc
RSU Pharm Alcohol/Psycho Drugs
Question | Answer |
---|---|
Scientific Name for Alcohol | Ethanol (EtOH) Ethyl Alcohol Grain Alcohol |
Alcohol effects on: CNS, Vascular, GI, Renal, Nutritional | CNS- Depresses Vascular- Dialation GI- Secretion Renal- Increase actvity Nutritional- Empty cals & vit. deficiencies |
Scientific Name for Wood alcohol (moonshine) | Methanol |
Increases appetite & increase inflamation of gastric acids | Alcohol |
Alcohol metabolised by ? | Liver |
Rate of alcohol metabolism | 10-15 mL/hr |
Stage of alcohol metabolism | Alcohol-> acetaldehyde-> acethl coenzyme A |
Acetaldehyde effect on body | makes you vomit |
Describe Disulfiram (Antabuse) mechanism | Stops conversion of acetaldehyde to acethl conemzyme A...so they vomit |
Acute Adverse effects of Alcohol | CNS depression (impaired speech, ataxia, blurred vision, loss of memory, severe depression may lead to stupor & coma Cold clammy skin, increase HR, decreased temp |
Chronic adverse effects of Alcohol | Fatty liver/cirrhosis Tolerance & dependence (withdrawal syndrome) Often Vit. B deficient Malnutrition/vit deficiency |
Alcohol cautions & contraindications | Intoxication can resemble head injury, diabetic coma, overdose Potentiation of centrally acting depressants Hepatic/renal disease, ulcers, epilepsy, hyperacidity |
Alcohol Clinical indications | Topically: decrease temp, disinfectant OTC: cold remedies |
Alcohol uses | Antoseptic, cooling agent, neuronal lysis, Antidote (methanol poisoning, antifreeze injestion, huff carborator cleaner/paint |
Alcohol is #1 cause of ____________ in US | liver failure |
Ways to die of liver failure | Bleed to death, Poison yourself |
Mental illnesses | Psychoses (schizophrenia) Neuroses (Anxiety/tension) Affective disorders (severe depression, bipolar) |
Schizophrenia is | disordered thoughts, emotions, & behaviors |
Types of Schizophrenia | Paranoid, Catatonc (extremes:loopy to comatos state), Disorganized (funtional, problems w/ thought & speech |
Delusions | truely believe |
Hallucinations | sensory but small doubt |
Schizophrenia: Types of delusions | Persecutory (Stocked, tricked) Referential (sublimial messages from TV) Somatic (fake illness) Religious (talked to God) Erotamatic (social delusions, believe in a relationship, but not) Grandiose (always one up you, believe what they are saying is t |
Neurosis: Generalized Anxiety Disorder Symptoms | Constant worry, restless, difficulty concentrating, irritable, insomnia,SOB, tachycardia |
To be diagnosed w/ Generalized Anxiety Disorder what 2 things must happen? | Has to significantly alter your life & be present for 2 or more weeks |
Types of Depression | Exogenous aka reactive depression Endogenous (more serious) |
Cause of Exogenous depression | external factors usually self limiting |
Cause of Endogenous depression | orginates w/in individual usually requires meds |
Severe depression symptoms | feeling sad, irritable, loss of interest, insomnia, change in appetite, slow thinking, crying spells for no reason, frequent thoughts of death dying or suicide |
Bipolar Disorder classifications | Bipolar I, Bipolar II, Cyclothymia |
Bipolar I | extreme mania, longer periods of mania then depression |
bipolar II | Hypomania, longer periods of depression then mania |
Cyclothymia | mild form of bipolar (never extremes) hypomania & hyperdepression |
EPS | Extrapyramidal Side Effects |
EPS Dystonic reactioons | involuntary movements-face, mouth & tongue |
EPS Akathisia | can't sit still |
EPS Parkinsonism | rolling fingers jerky movements, symptoms of Parkinson |
Antipsychotic Drugs aka ? | Neuroleptics |
Functions of Antipsychotic drugs (Neuroleptics) | Suppress symptoms (thalamus, limbic system) Regulate neurotransmitters |
Nerotransmitters abbreviations: Dopamine Serotonin Histamine Acetylcholine | DA, 5.HT, H, ACh |