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Pharm-Cephalosporins
Cephalosporins
Question | Answer |
---|---|
Cephalosporin Clinical uses: | Cystitis, skin infections, pyoderma and soft tissue infections; mastitis, shipping fever and pneumonia in LA |
Cephalosporin 2 important advantages over penicillin: | Active agains penicillinase producing bacteria, effective against some gram - bacteria as well as gram positive (Broad Spectrum) |
Cephalosporin -static or -cidal | Bactericidal |
Cephalosporin Spectrum of Activity | Broad |
Cephalosporin Toxicity | Non-toxic |
Cephalosporin Penicillinase Resistance | Resistant - Effective against all staph |
Cephalosporin Cephalosporinase Resistance | Suseptible |
Cephalosporin Excretion | Kidneys |
Cephalosporin Metabolism | Liver |
Cephalosporin Examples: | Simplicef, Convenia, Cefazolin/Ancef/Kefzol, Excenel, Naxcel, Cefa-Drops, Cefa-Tabs, Cefa-Lak. |
What Cephalosporin form is used intramammary? | Cefa-Lak |
What Cephalosporin form is available only for dogs? | Simplicef |
Which Cephalosporin form must be given slowly? (Can cause nausea, seixuring and vomiting if too fast.) | Cefazolin |
Which Cephalosporin form is effective for 14 days? | Convenia |
Which Cephalosporin form is approved for lactating dairy animals? | Naxcel |
Other Cephalosporin dosage forms | Cefaclor/Ceclor, Cefepime/Maxipime, Cefotaxime/claforan, Cefotaxime/Claforan, Cefotetan/Cefotan, Cefoxitin/Mefoxin, Ceftazidime, Cephalothin, Cephradine, Cefpodoxime |
Cephalosporin Side Effects | Allergic reactions, rare bleeding disorders, seizures, v/d |