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Pharm-Tetracyclines
Tetracyclines
Question | Answer |
---|---|
Tetracyclines clinical uses/indications | Respiratory infections, dental disease, bacterial enteritis and UTI’s |
Tetracyclines Spectrum of Activity | Broad - Gram +, Gram - and rickettsial |
What Tetracyclines dosage form is used to treat Lyme disease, ehrlichiosis and rickettsial organisms? | Doxycycline |
Tetracyclines Toxicity | Non-toxic |
Tetracyclines Side effects | v/d |
Tetracyclines Administration | PO, parenterally or topically |
Tetracyclines Stability | Stable - needs to be kept cool |
Tetracyclines -static or -cidal | Bacteriostatic |
Tetracyclines Resistance | Increasing over time |
Tetracyclines Contraindications | Causes permanent yellow discoloration of teeth; not absorbed from GI if given with milk or antacids |
Tetracyclines Excretion | Kidneys |
Tetracyclines Metabolism | Very little metabolism in liver = EXCRETED IN THE ACTIVE FORM |
Tetracyclines Dosage forms | Tetracycline hydrochloric/Panmycin, Ocytetracycline/Terramycin, chlortetracycline/Aureomycin (LA), Doxycycline/Doxirobe |
Doxirobe gel is used to treat what condition? | Periodontal disease |
What are Tetracyclines effective against besides bacterial organisms? | rickettsial organisms |