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Macrolides anti
Question | Answer |
---|---|
Macrolides may be? | bacteriostatic or bacterialcidal depending on the concentration in the infected tissue. |
macrolides they are? | effective against gram positive bacteria. |
macrolides MOA is | inhibits or kills bacteria by interfering with RNA protein synthesis within the bacteria. they act against multiplying bacteria. |
Macrolides are used to treat | penicillin allergy such as prophylaxis against rheumatic fever, syphilis, gonorrhea,chlamydia conjunctivitis( newborn) |
side effects of macrolides are | GI discomfort- nausea, vomiting, diarrhea, phlebitis at the iv infusion- erythromycin , hepatotoxicity- nausea, abdominal pain, cramps, fever and allergic reactions. |
Macrolides Monitor for | pt with renal disease, increased digitalis levels if pt is on digoxin, Pt INR( increased effects of anticoagulants) codamin INR 2.0-3.0 therapeutic level |
Azithromycin | Zithromax |
Clarithromycin | Biaxin, XL |
Erythromycin base | E-mycin - take around the clock |