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Lower Resp Infex

Pharm I

QuestionAnswer
What are the LRI? Pneumonia (CA, HCA), acute bronchitis, AECB; influenza, SARS, anthrax
Most cases of acute bronchitis are viral, what are the poss bacterial causes? Mycoplasma pneumoniae, chlamydia pneumoniae, bordatella pertussis
What are the anti-pyretics and analgesics? Ibuprofen, ASA, acetaminophen
What is the effect of OTC cold meds for acute bronchitis? Are counterproductive; most have decongestant/anti-hist combo=dries out secretions, so it's even harder to cough stuff up/out!
If fever & chills are present in a pt w/acute bronchitis, what should you do? CXR (to r/o pneumonia)
With severe AECB, usually see? ^dyspnea, ^sputum viscosity or purulence, ^sputum volume
What is the MC infectious cause of death in US? CAP
Mechanism of infection for CAP? -Inhalation of aerosolized particles -Seeding via the bloodstream from an extra-pulm infection -Aspiration of oral-pharyngeal contents
Which pathogen for CAP presents w/rust colored sputum, rapid onset fever, high WBC, lobar consolidating on CXR? Strep pneumoniae
Which CAP pathogen presents w/ slow course, non-productive cough, WBC NL or slightly^ Mycoplasma pneumoniae "Walking pneumonia"
Which CAP pathogen presents w/ pleuritic CP, poss hemoptysis, ^LFTS, hypoNA+? Legionella pneumoniae
How do you determine place of therapy for a CAP pt? CURB-65 score (>1 = inpt)
Explain CURB-65? Confusion=1pt BUN>19=1pt RR>30/min=1pt BP<90/60=1pt Age>65=1pt
What are the criteria to switch someone from IV to PO abx? -Hemodynamically stable -Improving clinically (cough&dyspnea) -Able to ingest meds -Normally fxning GI tract
What are the 1st & 2nd most common nosocomial infex in the US? 1. UTI 2. HA-pneumonia
Created by: 572680793
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