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Unit III Pharm
Things I Keep forgetting
Question | Answer |
---|---|
Spectrum of Activity for Metronidazole | Anaerobes and Parasites |
Medications that treat H. pylori | Metronidazole |
Drug that has Disulfiram-like effects | Metronidazole |
Trade name for metronidazole | Flagyl |
MOA of Metronidazole | Reeactive metabolite damage of DNA and other molecules |
Drugs that need renal adjustment | PCN's Cephalosporins, Vancomycin Fluroquinolones TMP/SMX Clarithromycin |
Drugs with ototoxicity and nephrotoxicity | TMP/SMP and Aminoglycosides |
Drugs that cause False + fever | B.lactams, penicillins, cephs, salicylates, phenytoin |
5 Intracellular pathogens | Neisseria Mycoplasm Chlamydia Legeionella Ureaplasm |
3 atypical pneumonia pathogens | mycoplasms legionella chlamedia species |
Most important pathogen in intra-abdominal infections | pseudomonas |
Useful for exercise-induced asthma when taken 30m prior to exercise | LABA's |
Use of leukotriene modifiers | asthma and allergic rhinitis exercise induced asthma` |
SE's of SABA's | Tremor, ^HR, palpatations |
Indications for Omalizumab | >12 yo, + skin test to perennial aeroallergens moderate-severe symptoms |
What is primatene? | sm doses of epinephrine: OTC mist and tablets works < 1 hr |
5 R's in smoking cessation | revalance, risks, rewards, roadblocks, repetition |
What Fagerstrom score is more serious? | 6 or greater, indicates ^ withdrawl sxs and more difficult to quit |
Drug Interactions w/ Bupropion | Carbamazepine, Cimetidine, MAO inhibitors |
Drugs given through DPI's Diskus | Fluticasone & Advair |
DPI's Aerolizer | Formoterol |
DPI's HandiHaler | Tiotropium |
Purpose for Spacers? | Allows evaporation of propellant b4 inhalation (no real clinical benifit) |
Nebulized products | Beta agonists, corticosterioids, anticholinergics |
ACT guidelines | Asthma Control Test >20 well controlled 16-19 not well controlled <16 poorly controlled |
Empiric Therapy based on what | likely pathogens at site of infection patient hx local susceeptibility |
Penicillin MIC values | Sensitive: /2.0 |
Tx for CA-MRSA | TMP/SMX, Clindamycin, Doxycycline |
Doxycycline tx's | CA-MRSA, CA-pneumonia, DOC: early lyme dz |
Tx for H. pylori | A. T. M Amoxacillin Tetracycline Metronidizole |
Chelation occurs w/ what drugs | FQ's and Doxy |
What drug interacts with most food | Erythromycin |
Common bacterial pathogens for Acute bronchitis | Mycoplama P. Chlamydia pneumonia Bordetella pertussis |
Pathogens for HAP | P Pseudomonas. S. Staph E. E. coli K. Klebsilla Acinetobacter |
Pathogens for CAP | Mycoplasm pnemonia clamydia legionells |
Pathogens for acute bronchitis | mycoplama chlamydia bordetella pertussis |
Pathogens for AECB | C. and M. pneomonia H. flu S. pneumonia M. Cat |
uncommon sxs of AECB | fever chills |
CA-pnemonia Outpatient tx for health individual | Macrolide or Doxycyline althernative |
CAP comorbitity Outpatient tx or ABO with last 3 m or >25% Macrolide resistance to s. pneumo | Resp. FQ Macrolide + B-lactam(high dose amoxacillin or Augmentin) Alternative to macrolide is doxycycline Alternative beta-lactams include ceftriaxone (Rocephin), cefpodoxime (Vantin), cefuroxime axetil (Ceftin) 500 mg bid |
CA-MRSA tx | Bactrum Clindamycin Doxycycline |
When is zanamivir CI | those w/ underlying airway dz (inhaled) |
Amantadine (Symmetrel®) & Rimantadine (Flumadine®) tx & SE | Influenza A, psychological effects, |
What is SARS | Severe acute respiratory syndrome |
Three types of anthrax infection | GI, inhalation, cutaneous (95%) |
Tx of inhalation anthrax | Cipro, Leviofloxacin, or doxycycline PLUS CLindamycin and/or rifampin |