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dleary Ch.3
para vs sympathetic
Question | Answer |
---|---|
Heart | Parasympathetic Effect-decreases rate and contractile force Sympathetic effect- increases rate and contractile force. |
Lungs | Parasympathetic effect- Bronchoconstricts Sympathetic effect- Bronchodilates |
Eyes | Parasympathetic effects-Pupil constriction Sympathetic effects-Pupil dilation |
Hair muscles | Parasympathetic effects-Relaxes Sympathetic effects -contracts and causes hair to stand on end (piloerection) |
Gastrointestinal | Parasympathetic effect- increases digestion sympathetic effect- decreases digestion |
urinary | Parasympathetic effect- Constricts bladder sympathetic effect- relaxes bladder |
Adgernergic receptors | |
Alpha 1 | Tissue-Vascular smooth muscle,pupil,pilomotor smooth muscle. Action- contracts, dilation (mydriasis), goose bumps. |
Beta 1 | Tissue- heart Action- stimulates rate and force |
Beta 2 | Tissue- Respiratory, somatic motor ( voluntary muscle) Action- Bronchodilates, tremors |
Dopamine | Tissue- Renal Action- Relaxes arteries |
Cholinergic agonist and indications | |
Direct acting- stimulates cholinergic receptors Bethanechol | indication- urinary retention |
Direct acting-stimulates cholinergic receptors Succinylcholine | indications- neuromuscular blockade- intubation |
Direct acting-stimulates cholinergic receptors Pilocarpine | indications-Glaucoma |
indirect-acting-decreases AChE activity Neostigmine | Myasthenia gravis |
indirect-acting decreases AChE activity- Pyridostigmine | Reversal of neuromuscular blockade |
indirect-acting decreases AChE activity- Malathion | Insecticide |
indirect-acting decreases AChE activity-nerve gas | Chemical Warfare |
Anticholinergic drug class | |
catagory and function- antimuscarinics- increases heart rate and bronchodilation | drug- Atropiine ipratropium brormide (atrovent) |
Nicotinic blockers-at preganglionic sites- prevent nervous transmission | drug- hexamethonium |
Sympathomimetic drugs | |
Catecholamines- Epinephrine | indications- anaphylaxis |
catecholamines- norepinephrine | indications - hypotension |
catecholamines- dopamine | indications- shock |
catecholamines- dobutamine | indications- shock, heart failure |
phenylephrine | indications- nasal decongestant. hypotension |
albuterol | indications- asthma |
sympatholytic drug sub group | |
alpha-blocker- drug- Doxazosin | indications- hypertension, benign prostate hypertrophy |
Beta-blocker- drug- propranolol | indication- hypertension |
Cholinergic/Parasympathomimetic | drugs that stimulate or mimic the parasympathetic receptors |
Anticholinergic/ Parasympatholytics | drugs that block parasympathetic receptors |
Adrenergic/sympathomimetics | drugs that stimulate or mimic the sympathetic receptors |
Antiadrenergic/sympatholytics | drugs that would antagonize the sympathetic response. |