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Autonomic Drugs
Drugs and classes
Question | Answer |
---|---|
Neostigmine | Cholinergic Agonists (AChE Inhibitors) |
Neostigmine | Increase Bladder Motility Treat Myasthenia gravis reverse NM blockade |
Physostigmine | Cholinergic Agonists (AChE Inhibitors) |
Physostigmine | Glaucoma Atropine Overdose |
Edrophonium | Cholinergic Agonists (AChE Inhibitors) |
Edrophonium (tensilon) | dx of myasthenia gravis |
Organophosphates | Cholinergic Agonists (AChE Inhibitors) |
Echothiophate, DFP, Soman, sarin, tabum, parathion, malathion | organophosphates |
2-PAM | muscarinic antagonist (use within 3 hrs) |
Atropine | muscarinic antagonist |
Ipratropium | muscarinic antagonist |
Tiotropium | muscarinic antagonist |
Ipratropium | COPD/acute asthma attacks |
Tiotropium | COPD/acute asthma attacks |
Tolteridine | muscarinic antagonist |
Tolteridene | used to treat overactive bladder |
Lomotil | Atropine + opioid to treat diarrhea |
Tropicamide | muscarinic antagonist |
Homatropine | muscarinic antagonist |
Tropicamide | mydriasis |
Homatropine | mydriasis |
Atropine | Low dose- salivary glands, sweat glands, bronchioles high dose- GU/GI CNS at high doses |
Atropine | muscarinic antagonist |
Scopolamine | muscarinic antagonist |
Scopolamine | Motion sickness |
Phenlyepherine | Alpha 1 agonist |
Clonidine | alpha 2 agonist |
Dobutamine | beta 1 agonist |
albuterol | beta 2 agonist |
NE | pulse pressure unchanged |
Epi | pulse pressure increased |
Epi | low dose- vasodilation (beta) high dose- vasoconstriction (alpha) |
Epi | vasocontrictor- for anaphylactic shock bronchodilator- for severe asthma attack |
Ephedrine | decongestant hypotensive emergency |
pseudoephedrine | decongestant mydriasis |
clonidine | alpha 2 agonist decreases sympathetic output decreases peripheral resistance and CO treat HTN |
Isoproterenol | beta 1 & 2- increased rate and contraction of heart, vasodilation |
Dobutamine | beta 1 agonist increased contractility of heart used for stress testing |
Dopamine | treat cardiac shock |
Amphetame/tyramine/cocaine/antidepressants | increased NE |
phentolamine | alpha antagonist (1 & 2) |
phentolamine | decrease peripheral resistance and BP reflex tachycardia alpha 2 block increases NE release, more tachycardia |
phenoxybenzamine | alpha antagonist |
phenoxybenzamine | irreversible alpha blockade used for pheochromocytoma |
prazosin | alpha antagonist (Alpha 1) vasodilation less tachycardia (no alpha 2 block) |
terazosin, doxazosin | alpha 1 blockers tx for BPH postural hypotension |
Tamsulosin | alpha 1A antagonist BPH |
Yohimbine | alpha 2 antagonist increases NE release |
propanolol | non-selective beta blocker |
propanolol | decreases mortality after MI treat angina CHF bronchoconstriction |
timolol | glaucoma caution in asthma |
metoprolol | beta-1 selective blocker |
atenolol | beta-1 selective blocker |
bisoprolol | beta-1 selective blocker |
nebivolol | beta-1 selective blocker |
esmolol | beta-1 selective blocker |
betaxolol | beta-1 selective blocker |
nebivolol | vasodilation due to NO release |
esmolol | short acting |
betaxolol | glaucoma safer than timolol, less bronchoconstriction |
Labetalol | beta and alpha blocker for HTN emergency decreases peripheral resistance (alpha 1 block) and prevents tachycardia (beta 1 block) |
carvedilol | beta and alpha blocker for HTN emergency decreases peripheral resistance (alpha 1 block) and prevents tachycardia (beta 1 block) |
pindolol | beta blocker with ISA |
carteolol | beta blocker with ISA |
penbutolol | beta blocker with ISA |
acebutolol | beta blocker with ISA |