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Drugs

Pharmacology for Nurses 3rd Edition

QuestionAnswer
-ase, -plase Thrombolytic agent (-ase usually indicates enzyme){alteplase, anisterplase, reteplase, streptokinase, tenecteplase}
-azole Antifungal antimicrobial {clotrimazole, edorazole, fluconazole, itraconazole,, ketoconazole, miconazole, variconazole}
cef-, ceph- Cephalosporin, antibiotic; check allergy to this class and penicillins {cefazolin, cephalexin, cefotetan, ceftazidime, ceftriaxone, many others}
-cillin Penicillin, antibiotic; check allergy {amoxicillin, nafcillin oxacillin, penicillin, piperacillin, ticarcillin, and many others}
-cycline Tetracycline,antibiotic {doxycycline, minocycline, tetracycline
-dipine Calcium channel blockers, antianginal, antihypertensive {amlodipine, felodipine, isradipine, nicardipine, Nifedipine, nisoldipine}
-dronate Biphosphonate, bone resorption inhibitor {alendronate, etidronate, pamidronate, risedronate}
-floxacin Fluoroquinolone, antibiotic {ciprofloxacin, levofloxacin, norfloxacin, sparfloxacin}
-micin, -mycin Aminoglycoside, antibiotic {gentamicin, kanamycin, neomycin, netimicin paromomycin, streptomycin, tobramycin} Does not include macrolide type antibiotics such as erythromycin, azithromycin, or clarithromycin
nite-, -nitr- Nitrate,vasodilator,antianginal {isosorbide dinitrate or monaonitrate, nitroglycerin}
-olo, -lol Beta adrenergic blocker, antihypertensive and/or antianginal {atenolol, betaxolo, bisoprolo, metoprolol, nadolol, propranolol, timolol
-parin Anticoagulant, heparin or heparinoid {ardeparin, dalteparin, danaparoid, enoxaparin heparin, tinaxapain}
-phylline Xanthine type of bronchodilator {aminophylline, theophylline}
-prazole GI proton pump inhibitor, antiulcer {lansoprazole, ameprazole}
-pril Angiotensin convert enzyme (ACE ) inhibitor, antihypertensive {benazepril, captopril enalapril, fosinopril, lisinopril moexepril, perindopril, quinapril, ramipril, trandolapril)
Sal-, -sal- Contains salicylate; check allergy to Salicylates or aspirin {salsalate (nonopioid analgesic), sulfasalazine (GI anti-inflammatory)}
-sartan Angiotensin II receptor antagonist, antihypertensive {candesartan, eprosartan, irbesartan, losartan, olmesartan, telminsartan, valsartan)
-sone, -lone, pred- Corticosteriod {betamethasone, cortisone, dexamethasone, prednisolone, prednisone,, triamcinolone, others}
-statin HMG-Coenzyme A reductase inhibitor, lipid lowering agent {atorvastatin, fluvastatin, lovastatin, pravastain, rosuvastatin, simvastatin}
Sulfa- sulfonamide, antibiotic; check allergy to sulfa {sulfacetamide, sulfadiazine, sulfamethoxazole, sulfisoxazole}
-terol Adrenergic type of bronchodilator {albuterol, bitolterol, formoterol, levabuterol, metaproterenol, pirbuterol, almeterol}
-tidine Histamine H2 antagonist (GI), antiulcer {cimetidine, famotidine, nizatidine, ranitidine}
-triptan Vascularheadache suppressant, serotonin (5-HT1) agonist {almotriptan, naratriptan, sumatriptan, zolmitriptan)
-vir Antiviral antiinfective {acyclovir, cidofovir, famciclovir, gangciclovir, valacyclovir, others}
-zepan, -zolam Benzodiazepine, antianxiety, sedative/hypnotic {diazepam, lorazepam, oxazepam, alprazolam. Midazolam}
-zosin Peripherally acting alpha-1 blocker, antihypertensive {doxazocin, prazosin, terazosin}
ac before meals
ACE angiotensin converting enzyme
ARB angiotensin II receptor blocker
ASA acetylsalicylic acid (aspirin)
Bid two times a day
cc cubic centimeter
COX cyclooxygenase
DMARD disease modifying antirheumatic drug
DPI dry powder inhaler
Gm gram
h,hr hour
HRT hormone replacement therapy
IM intramuscular(ly)
IV intravenous(ly)
kg kilogram
KVO keep vein open
l, L litter
MAOI monoamine oxidase inhibitor
MDI metered dose inhaler
mg milligram
ml,mL milliliter
NSAID nonsteroidal anti-inflammatory drug
OTC over-the-counter
pc after meals
PO oral, by mouth
PPD purified protein derivative
PR per rectum
PRN as needed
q every
qid four times a day
qod every other day
subQ/SQ subcutaneous(ly)
sl sublingual
stat immediately
tid three times a day
Therapeutic Serum Drug Level-acetaminophen (Tylenol) 0.2-0.6 mg/dL; toxic: > 5 mg/dL
Therapeutic Serum Drug Level-carbamazepine (Tegretol) 4-12 mcg/mL
Therapeutic Serum Drug Level-digoxin (Lanoxin) 0.5-2.0 ng/mL
Therapeutic Serum Drug Level-lidocaine (xylocaine HCI) 1.5-6.0 mcg/mL
Therapeutic Serum Drug Level-lithium (Eskalith) 0.5-1.5 mEq/L
Therapeutic Serum Drug Level-phenytoin (Dilantin) 10-20 mcg/mL
Therapeutic Serum Drug Level-procainamide (Pronestyl) 4-8 mcg/mL
Therapeutic Serum Drug Level-quinidine (Quinalgute) 2-6 mcg/mL
Therapeutic Serum Drug Level-salicylate (acetylasalicylic acid; Aspirin) 100-200 mg/L; toxic: >200 mg/L
Therapeutic Serum Drug Level-theophylline (Theo-Dur) 10-20 mcg/mL
Therapeutic Serum Drug Level-valproic acid (Dapakene) 50-100 mcg/mL
Therapeutic Serum Drug Level-vancomycin (Vancocin) 30-40 mg/mL (peak); 5-10 mg/mL (trough)
mcg microgram
mEq milliequivalent
ng nanogram
Antidote for-Acetaminophen (Tylenol) acetylcysteine (Mucomyst)
Antidote for-Anticholnergics physotigmine(Antilirium)
Antidote for-Benzodiazepines flumazenil (Romazicon)
Antidote for-Calcium channel blockers calcium chloride, calcium gluconate
Antidote for-cyanide or nitrate methylene blue (Urolene blue)
Antidote for-Digoxin (Lanoxin) digoxin immune fab (Digibind)
Antidote for-Heparin protamine sulfate
Antidote for-Iron deferoxamine (Desferal)
Antidote for-Insulin glucagon
Antidote for-Lead succimer (Chemet)
Antidote for-Opioids naloxone (Narcan); nalfemene (Revex)
Antidote for-Warfarin sodium (Coumadin) vitamin K (Aquamephton)
Mechanism of Action-Beta Blockers Decrease the heart rate and myocardial contractility, reducing cardiac output
Mechanism of Action-Diuretics Increase urine output and decrease fluid volume
Mechanism of Action-ACE Inhibitors Block formation of angiotensin II, causing vasodilation and block aldosterone secreations, decreasing fluid volume
Mechanism of Action-Angiotensin receptor blockers Prevent angiotensin II from reaching its receptors, causing vasodilation
Mechanism of Action-Calcium channel blockers Block calcium ion channels in arterial smooth muscle, causing vasodilation
Mechanism of Action-Direct vasodilators Act on the smooth muscle of arterioles, causing vasodilation
Mechanism of Action-Alpha1 blockers Inhibit sympathetic activation in arterioles, causing vasodilation
Mechanism of Action-Alpha2 agonists Decrease sympathetic inpulses from the CNS to the heart and arterioles, causing vasodilation
Created by: mj8792
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