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Pharm: GI Drugs: Def
Pharm: Kee Ch47: Drugs for GI Tract Disorders: Definitions
Question | Answer |
---|---|
Chemoreceptor trigger zone (CTZ) | Lies near medulla |
Vomiting center | In medulla |
Cannabinoids | Active ingredients in marijuana; approved from clinical use in 1985 to alleviate n/v resulting from cancer treatment |
Opiates | Decrease intestinal motility, thereby decreasing peristalsis |
Adsorbents | Coat the wall of the GI tract & absorb bacteria/toxins that cause diarrhea |
Cathartics | Used to eliminate fecal matter |
Purgatives | "harsh" cathartics that cause watery stool & abdominal cramping |
Osmotics | Hyperosmolar laxatives |
Selective chloride channel activators | Treats idiopathic constipation; activates chloride channels in lining of small intestine, leading to increase in intestinal fluid secretion & motility |
Emollients | Lubricants & stool softeners used to prevent constipation; decrease straining during defecation |