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Endocrine Medication
Meds
Question | Answer |
---|---|
cosyntropin (Cortrosyn) | anterior pituitary drug Anti-inflammatory effect Promotes renal retention of Na Used in the DIAGNOSIS of adrenocortical insufficiency...If given and there's no response then there is a problem w/the cascade. |
cosyntropin (Cortrosyn) Nursing implications, route | IM, SQ, IV, gel forms hydrate decrease Na intake avoid vaccinations |
cosyntropin (Cortrosyn) adverse effects, contraindications | edema, HTN Caution w/migraine HA, epilepsy, asthma |
Somatropin and Somatrem Growth Hormone | Anterior Pituitary...for children Mimic growth hormone Indications...inadequate secretion of endogenous GH...Hypopituitary dwarfism, HIV wasting |
Somatropin and Somatrem (growth hormone) nursing implications | Parents should keep growth journal Monitor therapeutic response rotate injection site |
Samatropin and Somatrem (growth hormone) adverse effects | HAhyperglycemia Hypothyroidism Inflammation at injection site Flu-like sx |
octreotide (Sandostatin) | Anterior Pituitary antagonizes the effect of natural GH |
octreotide (Sandostatin) indications | alleviates the sx of secretion of Vasoactive intestinal peptide(VIP), esopageal varices, acromegaly |
octreotide (Sandostatin) nursing implications | Gallbladder studies Assess liver/renal fx Monitor glucose |
octreotide (Sandostatin) adverse effects | HA fatigue increased or decreased glucose |
vasopressin action, class, indication | Posterior Pit...mimics natural ADH POWERFUL vasoconstrictor!!!! Diabetes Insipidus |
desmopressin action, class, indication | Posterior Pit...mimics natural ADH Tx for blood disorders, nocturnal enuresis Diabetes insipidus |
vaso+desmopressin adverse effects | increased BP fever HA Nausea tremors |
vaso+desmopressin therapeutic response | should reduce severe thirst and decrease urinary output |
levothyroxine (Synthroid, Levothyroid) Indications | synthetic thyroid hormone T4 Achieve a euthyroid condition Hypothyroidism Tx w/thryroidectomy |
levothyroxine (Synthroid, Levothyroid) contraindictations | recent MI adrenal insufficiency hyperthyroid (if overdosed) Cardiac dysrhythmia...MOST SIGNIFICANT |
levothyroxine (Synthroid, Levothyroid) nursing implications | baseline vs weight continue Tx during pregnancy Teach pt...take at same time Qday, do not switch brands w/out asking md. Do not take over-the-counter meds w/out approval. Therapeutic effects may take several months. |
methimazole (Tapaxole) propylithiouracil (PTU) thiomide derivatives | Antithyroid Prevent surge in thyroid hormones that occur during surgical or radioactive iodine therapy |
Antithyroid drugs adverse effect | Liver and bone marrow toxicity |
Antithyroid drug interactions | oral anticoagulants increased activity |
Antithyroid drugs nursing implications | Give w/food Same time Qday Avoid high amts of iodine (seafood, soy sauce, tofu, iodined salt) |
Glucocorticoids class | adrenocortical horomone |
mineralcocorticoid class | adrenocortical hormone |
adrenal steroid inhibitor class | adrenocortical hormone |
Adrenocortical Hormone contraindications | -Serious infections (except tuberculosis meningitis) Caution w/pt w/gastritis, reflux disease, ulcer disease, diabetes, cardiax/renal/liver dysfunction |
Adrenocortical Hormone Adverse Effects | HF, HTN, convulsions, Ha, vertigo, mood swings, nervousness, insomnia, growth suppression, mentrual irregularities, peptic ulcers, pancreatitis, abd distention, fragile skin, petechaie, ecchymosis,facial erythema, etc... |