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68wm6 p2 anti-infect Matching
Are macrolides broad or narrow spectrum?
Broad spectrum.
What may indicate renal toxicity in a PT on antifungals?
*Increased BUN (>40mg/dL) *creatinine (>3mg/dL)
What should be done with the feces while the PT is on antihelmintic drugs?
specimen must be sent to lab while warm & 1-3 weeks post tx
List 3 adverse effects of macrolides
*Rash, pruritus, urticaria, thrombophlebitis at IV site *Chest pain, palpitations, prolonged QT interval (rare) *GI upset, hepatotoxicity, pancreatitis *Headache, vertigo, tinnitus, hearing loss
What drug when taken with aminoglycosides increases the risk of ototoxixity and the hearing loss associated with it?
Loop diuretics (like lasix)
What may have additive CNS and nephrotoxicity with drugs causing similar adverse reactions?
Acyclovir
What are aminoglycosides indicated for?
Serious gram negative infections & specific gram positive cocci bacteria
List three adverse effects of sulfonomides
*Rash *STEVEN-JOHNSONS SYNDROME *Photosensitivity reactions *GI upset, hepatotoxicity, pancreatitis *Aplastic anemia, hemolytic anemia, thrombocytopenia
What are the contraindications of sulfonomides?
*Drug allergy to sulfonamides *Pregnant women at term *Infants less than 2 month old
What is aspartate aminotransferase (AST)?
test for liver damage. Low values are good, high values are bad.
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