| Question | Answer |
| T or F? Major warning signs of adrenal disease include abnormal BP, abnormal K, acid-base, urine dilution and unexplained weight change. | true |
| The two main sites of production of heme are: | Liver and bone marrow |
| A 34 yr old women presents with goiter, tachycardia and weight loss of 2 month duration. TSH is undetectable and free T4 is high. What tests are helpful in diagnosing the cause of hypothyroidism? | TSH, TSH receptor antibodies, and RAIU |
| The two main classes of porphyrias, according to symptoms are: | Neurological and cutaneous |
| The two main sites in the body for accumulation of excess porphyrins are: | Liver and the bone marrow |
| Polarographic methods of glucose assay are based on which principle? | Rate of oxygen depletion measured |
| Serum or plasma myoglobin levels are used as: | An early marker of acute myocardial infraction |
| Inherited disorders in which a genetic defect causes abnormalities in rate and quantity of synthesis of structurally normal polypeptide chains of the hemoglobin molecules are called | thalassemias |
| Estrogen influences the secretion of which hormones? | Growth hormone, prolactin, and Luteinizing hormone |
| increased intervascular hemolysis is indicated by a decrease in: | Haptoglobin |
| Characteristics of Gierke disease: | increased plasma lactate, hypoglycemia, and subnormal response to epinephrine |
| Primary route(s) of excretion for protoporphyrin (PROTO), uroprophyrin (URO), and coproporphyrin (COPRO) are: | URO excreted primarily in urine, PROTO in the feces and CORPRO in either |
| The relationship between precursors in yhe heme synthesis pathway and the type of porphyria resulting from excess buildup of these precursors is: | excess of early precursors causes neurological porphyrias and excess of late precursors causes cutaneous porphyrias |
| The biologically most active, naturally occurring androgen is: | Dehydroepiandrosterone |
| the definitive suppression test to prove autonomous production of growth hormone is: | Oral glucose loading |
| What is responsible for epinephrine production | cortisol |
| Secondary porphyrias not due to an inherited biochemical defect in heme synthesis can be distinguished from true porphyrias by measuring levels of: | Urinary ALA and PBG |
