Biochemistery of Hemoglobin; Bronchospasm Therapy Medications
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| show | cAMP (adenyl cyclase) & cGMP (guanyl cyclase)
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| show | cAMP-B2 andrenergic recepror sites are stimulated, uses Mg2+ to convert ATP to cAMP to result in Bronchodilation.cGMP - A-andrenergic receptors stimulated , coverts guanosine triphosphate (GTP) to cyclic GMP
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| What does the A-andrenergic blockade drugs do? | show 🗑
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| show | influences the biochemical event of adenyl cyclase activation causing brochodilation
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| show | influences the biochemical event prevents dehydration of cyclic AMP to 5-AMP, thus keeping it active longer which PREVENTS the chance of bronchoconstriction.
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| show | influences the biochemical event guanyl cyclase activation resulting in bronchoconstriction.
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| Describe the significance of antigen-antibody reactions on the surface of the mast cell? | show 🗑
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| ALBUTEROL( Ventolin,Proventil) | show 🗑
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| show | B2 stimulation; adenyl cyclase activation, increase in cyclic AMP
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| PIRBUTEROL(Maxair) | show 🗑
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| TERBUTALINE(Brenthine,Brieanyl) | show 🗑
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| EPINEPHRINE(Adrenaline) | show 🗑
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| show | Cholinergic Blockade;prevents guanyl cyclase activation,decrease cGMP
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| show | cholinergic blockade; prevents guanyl cyclase activation,decreses in cGMP
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| show | A-BLOCKADE(CARDIAC); PREVENTS guanyl cyclase, Deacrease cGMP
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| show | A-BLOCKADE;PREVENTS guanyl cyclase, decrease cGMP
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| show | LEUKOTRIENE MODIFIER;ANTI-INFLAMMATION,BRONCHODILATION
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| MONTELUKAST(Singulair) | show 🗑
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| ZILEUTON(zyflo) | show 🗑
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| CROMOLYN SODIUM(Intal) | show 🗑
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| show | BLOCKS antigen-antibody reaction; PREVENTS mast cell degranulation and mediator release
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| METHYLXANTHINES(Theophyline,caffene,Theobromide,Aminophylline) | show 🗑
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| show | BLOCKS cholinergic-induced bronchospasm,bronchodilatory action
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| show | B2 agonist stimlation during a bronchospasm
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| Relate the utility of cromolyn for the treatment of asthma. | show 🗑
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| Describe the make-up of methemoglobin? | show 🗑
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| show | I
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| Oxygen attachment on hemoglobin? | show 🗑
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| show | Teminal Amine group Globin portion
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| show | imidazole group on deoxygenated hemoglobin
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| show | Cooperativity ehances bonding of oxygen by increasing bonding potentional. Conversely, at the tissue level the unloading of oxygen molecule facilitates the release at oxygen at the other sited
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| show | body temp. , PaCO2, Arterial pH, 2-3-DPG
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| show | Effect of Carbon Dioxide or (H+) pn uptake and relase of oxygen from the hemoglobin(effect mild)
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| Define Haldane Effect: | show 🗑
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