Control of Glomerular Filtration Rate
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| What are 2 determinants of GFR? | MAP, AFFERENT Arteriole diameter
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| How would increased Sympathetic activity affect GFR? | Increase Sympathetic --> Vasoconstriction --> DECREASE GFR --> decrease Urine Output
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| How would decreased Symapathetic activity affect GFR? | decrease Sympathetic --> Vasodilation --> INCREASE GFR --> increase Urine Output
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| What effect would Hemorage have on GFR and why? | decrease Pressure --> decrease GFR --> conserve H2O and restore Blood volume
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| How do Epinephrine and Renin affect GFR? | Vasoconstricting agents - constrict --> DECREASE GFR
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| Where does Epinephrine come from? | Adrenal Medulla
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| Where does Renin come from? | secreted by the cells of the Juxtaglomerular Complex
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| What effect do vasodilating agents have on GFR? give an example. | dilate --> ^ GFR --> ^ UO
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| What 3 factors influence Afferent Arteriole diameter? | relative Sympathetic activity, Vasoconstricting agents, Vasodilating agents
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| How does age affect GFR? | DECREASE GFR - because of Atherosclerosis
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| How are BP and GFR correlated? | ^ BP --> ^ GFR and decrease BP --> decrease GFR
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| How is GFR measured? | Liters filtered per day - average 93 mm Hg
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| Where does MAP affect GFR? | Global - from the whole body
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| Where doe Afferent Arteriole diameter affect GFR? | Local = best - affect GFR moment to moment
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Created by:
Kristel
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