coagulation
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| coagulation | clot formation
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| clot formation | necesary for survival from injuries or surgery
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| hemostasis | stoppage of blood flow
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| thromboplastin | a substance that triggers the clotting mechanism
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| thrombin | converts soluble fibrinogen to insoluble fibrin
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| thrombus | a blood clot within a blood vessel
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| embolus | a mass of undissolved matter in the vessel
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| anticoagulants | used to prevent venous clotting
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| adverse reaction of an anticoagulant | hemorrhage
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| a specific drug of an low molecular weight heparin (LMW) | ardeparin
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| a specific drug of an low molecular weight heparin (LMW) | dalteparin (fragmin)
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| a specific drug of an low molecular weight heparin (LMW) | enoxparin (lovenox)
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| a specific drug of an low molecular weight heparin (LMW) | warfarin (coumadin)
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| warfarin | does not affect established clots, but does prevent further extenstion of formed clots
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| antidote of an hemorrhage | vitamin K
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| half-life | means drugs can be given less frequently
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| antiplalatnet | drugs are used to suppress the aggregation
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| aggregation | clumping or sticking together
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| ticlopidine (ticlid) | produces irreversible inhibition of platelet fibrin binding
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| clopidogrel (plavix) | mechanism of action is similar to ticlopidine
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| specific drugs of thrombolytics | alteplase (activase)
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| specific drugs of thrombolytics | steeptokinase (stretase)
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| specific drugs of thrombolytics | tenecteplase (TNKase)
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| topical hemostatics | gelatin or cellulose sponges
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| topical hemostatics | usually used to control bleeding that occurs during oral, dental, opthalmic
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| hyperlipidemia | a metabolic disease characterized by increased concentrations of cholesterol and triglycerides
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| for a thrombolytics to work | it must be given every 1 to 6 hours
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| a primary lipoprotiens | HDL-high density lipoprotiens - good cholesterol
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| a treatment of hyperlipemia | diet
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| a treatment of hyperlipemia | bite acid sequestants
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| bite acid sequestrants | bind to bite acids in the intestines, preventing the absoption and producing insoluable complex that is excreted
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| a specific drug of hyperlipidemia | cholestryamine (questran)
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| HMG | COA reductase inhibator
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| HMG | prefered to as "statins"
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| treatment of hyperlipidemia is | lovastain (mevacor)
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| liquid drugs | are supplied in pre-filled syringes, ampules or glass/ plastic vials
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| MEQ | milliequivalent
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| IVPB | IV piggy bank
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| KVO | keep vien open
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| STAT | immediately
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| LVP | large volume parenteral
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| NaCl | sodium chloride
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| Swfi | sterile water for injection
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| angiotensin II | a ptent casoconstrictor and stimulates the production of aldosterone which increase blood pressure
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| primary function of kidneys | to maintain the balance of water, electrolytes, acids and bases
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| divretics | block the re-absorption of sodium and chloride inthe kidneys which aids in controlling blood pressure
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| osmotic divertics | mannitol (osmitrol)
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| thiazide divertics | all drugs in this class have equivalent potency but differ in onset, peak and duriation of action (DOA)
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| loop divretics | furosemide (lavix)
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| adverse effect of a loop divretic | hyperglycemia
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| potassium sparing divretics | spironolactone (aldactone)
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| ACE-1 | inhibits the formation of angiotensin and reduces the action of the AA system
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| AA ___system | renin-angiotensin-aldosterone
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| a specific drug of an ACE-1 inhibator | captopril (capoten)
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| ACE-1 | angiotensin converting enzyme inhibator
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| ACE -2 inhibators | block the receptors for angiotensin
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| a specific drug of ana ACE-2 inhibator | losartan (cozaar)
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| sympatheltic blocking agents | stimulate the central alpha receptors and decreases the outflow of norepinephrine
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| a specific drug of an sympathetic blocking agent | clonidine (catapres)
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| indication of a thrombolytics is | lysis (breakdown) of pulmonary embolism or coronary artery thrombis during an acute MI
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| atherosclerosis | a fatty plaque deposits in the lining of the arteries
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| VLDL | very low density lipoprotiens
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| LDL | low density lipoprotiens
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| fibrin | forms a network of threats that entrap RBC and platelets to form a clot
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| anticoagulants works by | inhibition of preformed clotting factors, prevention of synthesis of normal clotting factors
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