Critical care - shock, sedation, respiratory support etc.
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show | 70-100 mmHg
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significance of lactic acid levels in critical care | show 🗑
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SVR in sepsis vs hypovolemic shock | show 🗑
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show | 7.4 (7.35-7.45)
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normal pCO2 | show 🗑
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show | 80-100 mmHg
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show | 22-26 mEq/L
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Normal SaO2 | show 🗑
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metabolic acid base disorders are illustrated by changes in what blood gas measurement | show 🗑
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show | pCO2 - elevated when acidiv, decreased in alkalosis
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what is the compensatory mechanism for metabolic acid base disorders | show 🗑
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how does metabolic acid base compensate for underlying respiratory acid base | show 🗑
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MUDPILES | show 🗑
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F-USED CARS | show 🗑
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show | fluid resucitation. either blood, colloids or crystalloids. if still hypotensive may need pressor support but this wont work without adequate fluid replacement.
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show | fluid resuscitation to achieve HR, MAP and CVP goals. if SvO2 still not at goal may give more fluid. vasopressors to achieve MAP of 65+ if needed. place ART line rather than BP cuff for monitoring. if cardiac dysfunction may need inotropes
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Options other than phentolamine for extravasation. | show 🗑
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preferred vasopressors for septic shock | show 🗑
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preferred inotropes for septic shock | show 🗑
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show | triglycerides, BP, calories from IV lipid 10% 1 kcal/ml. S/sx of PRIS
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show | Propofol related infusion syndrome. associated with infusion rates of >50mcg/kg/min. results in metabolic acidosis, rhabdomyolysis, hyperkalemia, kidney failure, cardiac arrest, bradycardia
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show | propofol and precedex. Precedex can use load in surgery though.
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show | 0.2-0.7 mcg/kg/hr but some evidence supports going up to 1.5
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show | nausea, vomiting, agitation. occur after prolonged use, 1 wk
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show | CAM-ICU and ICDSC
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drugs associated with delerium | show 🗑
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show | haloperidol - but no evidence to support
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show | intubated pts with persistent hypoxia despite adequate sedation and analgesia. control intracranial hypertension in pts with neurological injury from TBI
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show | bed sores and corneal ulcers, critical illness polyneuropathy, masks inadequate sedation and analgesia, masks seizure, inc risk for VTE
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show | prolonged muscle weakness or paralysis once paralytic is removed
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Train of four | show 🗑
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show | hypermag, hypo calcemia, hypokalemia
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show | hypercalcemia, hyperkalemia
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show | aminoglycosides, corticosteroids, clinda, tetracyclines, CCBs, Type Ia antiarrhythmics, lasix, Lithium
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show | aminophylline and theophylline, CBZ, phenytoin.
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treatment target for glucose in the ICU | show 🗑
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risk factors for stress ulcers that ALONE warranting drug therapy | show 🗑
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show | head or spinal cord injury, 35%+ burn, hypoperfusion, acute organ dysfunction, GI bleed in last year, high dose corticosteroid, liver failure with associated coagulopathy, postop transplant, AKI, major surgery, multiple trauma
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show | decrease BP over days
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key difference between hypertensive urgency and emergency | show 🗑
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what are the end organ complications that can occur with hypertensive emergency | show 🗑
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show | decrease DBP to 100-110 or decrease MAP by 25% within 30-60 minutes
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drugs of choice for hypertensive emergency - tailored by disease state | show 🗑
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warfarin INR goal in patients with PAH for precention of catheter thrombosis and VTE | show 🗑
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