A deck of flashcards for Undergraduate Study of Biology.
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Translation | show 🗑
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show | Messenger RNA (mRNA) and transfer RNA (tRNA). mRNA is translated into a protein with the help of tRNA.
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show | An adaptor molecule composed of RNA, that serves as the physical link between the mRNA and the amino acid sequence of proteins. They are not identical, each carrying a specific AA and has an anticodon on the other end.
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show | A sequence of three nucleotides forming a unit of genetic code in a transfer RNA molecule, corresponding to a complementary codon in messenger RNA.
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Conditions for accurate translation | show 🗑
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Wobble | show 🗑
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Ribosomal RNA (rRNA) | show 🗑
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show | The P site, A site and E site.
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The P site | show 🗑
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The A site | show 🗑
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The E site | show 🗑
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show | Initiation, Elongation and Termination.
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show | A stage of translation that brings together mRNA, a tRNA with the first amino acid, and the two ribosomal subunits (rRNA). A small ribosomal subunit binds with mRNA and a special initiator tRNA.
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show | AUG
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Elongation stage in translation | show 🗑
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Termination stage in translation | show 🗑
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Polyribosome (polysome) | show 🗑
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Two populations of ribosomes in the cell | show 🗑
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Are ribosomes identical? | show 🗑
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Free ribosomes | show 🗑
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show | Makes proteins of the endomembrane system and proteins that are secreted from the cell.
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show | Polypeptide synthesis always begins in the cytosol.
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show | Only when the polypeptide signals the ribosome to attach to the ER.
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Signal peptide | show 🗑
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show | Changes in the genetic material of a cell or virus.
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Point mutation | show 🗑
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Two general categories of point mutations | show 🗑
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show | Replaces one nucleotide and its partner with another pair of nucleotides.
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Silent mutations | show 🗑
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Missense mutations | show 🗑
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Nonsense mutations | show 🗑
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show | Where insertion or deletion (addition or losses) of nucleotide pairs in a gene alters the reading frame of the RNA.
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Mutagen | show 🗑
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show | Bacteria; simultaneously. Eukarya: Separated by nuclear envelope. Archaea: Likely coupled.
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Defining a "Gene" | show 🗑
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show | A region of DNA that can be expressed to produce a final functional product, either a polypeptide or an RNA molecule.
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show | The process by which DNA directs protein synthesis, which includes two stages: transcription and translation.
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show | Evidence from the study of metabolic defects and nutritional mutants in Neurospora.
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show | The intermediate between genes and the proteins for which they code.
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Transcription | show 🗑
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show | The initial RNA transcript from any gene.
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show | On a triplet code: a series of non-overlapping, three nucleotide words. These triplets are the smallest units of uniform length that can code for all the amino acids.
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Template strand | show 🗑
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show | mRNA base triplets, read in the 5' to 3' direction during translation. It must be read in the correct reading frame(groupings) in order for the specified polypeptide to be produced.
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show | The enzyme which catalyzes RNA synthesis by prying the DNA strands apart and hooks together the RNA nucleotide. RNA synthesis follows the same base-pairing rules as DNA, except uracil substituted for thymine.
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show | The DNA sequence where RNA polymerase attaches
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Transcription unit | show 🗑
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show | Initiation, Elongation and Termination.
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show | Promoters signal the initiation of RNA synthesis.
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How the initiation stage of transcription happens in bacteria? | show 🗑
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How the initiation stage of transcription happens in Eukaryotes? | show 🗑
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Transcription initiation complex | show 🗑
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show | A promoter which is crucial in forming the initiation complex in eukaryotes.
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show | RNA polymerase moves along the DNA, untwisting the double helix, 10 - 20 bases at a time.
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show | Transcription progresses at a rate of 40 nucleotides per second in eukaryotes.
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Termination stage in transcription for bacteria | show 🗑
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Termination stage in transcription for eukaryotes | show 🗑
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show | These non-coding regions, they are also called intervening sequences.
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Exons | show 🗑
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RNA splicing | show 🗑
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show | Consists of a variety of proteins and several small nuclear ribonucleoproteins (snRNP). It interacts with certain sites along an intron, releasing the intron and joining together the two exons that flanked the intron.
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Ribozymes | show 🗑
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show | It can form a three-dimensional structure because its ability to base pair with itself. Some bases in RNA contain functional groups. RNA may hydrogen-bond with other nucleic acid molecules.
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show | Variations from genes that can encode more than one kind of polypeptide, depending on which segments are treated as exons during RNA splicing.
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Domains | show 🗑
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show | The evolution of new proteins.
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