SPC Cardiopulmonary Physiology Final Exam Unit 5 Review
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| Anatomical location of Peripheral Chemoreceptors? | Aortic Arch & Carotid Sinus
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| Which nerve innervates the carotid bodies? | Glossopharyngeal (IX)
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| Which nerve innervates the aortic bodies? | Vagus (X)
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| The chemical stimuli for Peripheral Chemoreceptors? | Low O2 Tension <60 & Low pH
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| Anatomical location of Central Chemoreceptors? | Ventrolateral Surface of the medulla immersed in CSF
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| The chemical stimuli for Central Chemoreceptors? | High CO2 Tension & Low pH
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| How is ventilation effected in chronic respiratory acidosis? | 1. HCO3 increases in CSF and the central chemoreceptors are obtunded (dull).
2. Low PaO2 stimulated the peripheral chemoreceptors establishing hypoxic drive.
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| How is ventilation effected in severe metabolic acidosis (Ketoacidosis)? | H+ stimulate the central and peripheral chemoreceptors causing a Kussmaul's breathing pattern and PaCO2 drop in the 20's
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| What is the control center for ventilation? | Cerebral Cortex
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| VE Changes: PaCO2 | With normal PaO2, VE increases 3L/min for each mmHg rise in PACO2.
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| VE Changes: PaO2 | VE increases dramatically when the PaO2 falls below 60mmHg.
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| VE Changes: pH | Acute Acidosis stimulates Peripheral Chemoreceptors & VE increases. The lower the pH, the greater the VE increases.
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