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Ch 16 Adaptive Immunity

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Term
Definition
CLONAL SELECTION   The development of specific B and T cells against a specific antigen.  
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Adaptive Immunity   A vertebrate’s ability to recognize and then mount a defense against specific invaders and their products.  
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ANTIBODIES   Proteins that are made in response to an antigen.  
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ANTIBODY DEPENDENT CELL MEDIATED CYTOTOXICITY   The killing of antibody-coated cells by natural killer cells and leucocytes.  
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ANTIBODY TITER   This is a reflection of the antibody-mediated humoral response and determines the relative amount of antibody in the serum.  
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ANTIGEN   Any substance that causes antibody formation and reacts only with its specific antibody.  
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ANTIGEN PRESENTING CELLS   These cells display a single antigen to T cells.  
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ANTISERUM   Blood-derived fluids containing antibodies.  
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ARTIFICIALLY ACQUIRED ACTIVE   This type of immunity results from vaccination.  
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ARTIFICIALLY ACQUIRED PASSIVE   This type of immunity involves the transfer of preformed antibodies by injection  
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Autoantigens   Self-antigens  
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B CELLS   These cells manufacture specific antibodies.  
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CELLULAR IMMUNITY   Immune response mediated by T cells.  
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CHEMOKINE   A cytokine that induces, by chemotaxis, the migration of leukocytes into infected areas.  
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CYTOTOXIC T LYMPHOCYTE   A specialized T cell that destroys infected cells presenting antigens.  
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Endogenous antigens   Produced when protozoa, fungi, bacteria, and viruses reproduce inside a body’s cells.  
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EPITOPES   Antigenic determinants.  
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Exogenous antigens   Include toxins and other secretions and components of microbial cell walls, membranes, flagella, and pili.  
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GAMMA GLOBULINS   Immune serum globulins.  
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Helper T cells   These cells help to regulate the activity of B cells and cytotoxic T cells during an immune response.  
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HUMORAL IMMUNITY   Immune response mediated by B cells.  
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IGA   This immunoglobulin is found on mucosal surfaces.  
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IGD   This immunoglobulin is present on the surface of B cells.  
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IGE   This immunoglobulin is involved in allergic reactions.  
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IGG   This is the most abundant antibody in the serum.  
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IGM   This immunoglobulin is the first antibody produced in response to the initial infection.  
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IMMUNOGLOBULINS   Another name for antibodies.  
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INFLAMMATION   A host response to tissue damage characterized by redness, pain, heat and swelling.  
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INNATE RESISTANCE   The resistance of an individual to diseases that affect other species and other individuals of the same species.  
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Lymph   A colorless, watery liquid similar in composition to blood plasma.  
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Major Histocompatibility Complex   A cluster of genes which codes for the major histocompatibility antigens.  
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MONOCLONAL ANTIBODY   A specific antibody produced in vitro by a clone of B cells hybridized with cancerous cells.  
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MONOMER   The simplest molecular structure of a bivalent antibody.  
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NATURAL KILLER CELL   A lymphoid cell that destroys tumor cells and virus-infected cells.  
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NATURALLY ACQUIRED ACTIVE   This type of immunity can be obtained by exposure to antigen during daily life.  
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NATURALLY ACQUIRED PASSIVE   This type of immunity results from the natural transfer of antibodies from a mother to her infant.  
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Regulatory T cells   Previously known as suppressor T cells, also interact with other immune cells and produce different cytokines than helper T cells.  
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SECONDARY RESPONSE   Memory response.  
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T CELL   A type of lymphocyte that is responsible for cell-mediated immunity  
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Primary Response   The slow and limited immune response to a first encounter with an unfamiliar antigen  
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