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Ch 17 Immunizations and Immunoassays

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Term
Definition
ACELLULAR   Also known as a subunit vaccine.  
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ADJUVANTS   Chemicals added to vaccines to improve the effectiveness of antigens.  
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AGGLUTINATION   Involve the use of IgG or IgM to form large, interlocking aggregates (lattices) with particulate antigens.  
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ATTENUATED   A live, but weakened, microbe.  
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COMPLEMENT FIXATION   The process in which complement combines with an antigen-antibody complex.  
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CONJUGATED   Vaccines made by combining a weak immunogen with a protein.  
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ENZYME LINKED IMMUNOSORBENT ASSAY   ELISA.  
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FLUORESCENT ANTIBODY   These techniques combine fluorescent dyes with antibodies to detect the presence of specific antibodies in the serum or the presence of microorganisms.  
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HEMAGGLUTINATION   Agglutination reaction involving the clumping of red blood cells.  
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HERD IMMUNITY   Protection against illness provided to a population when a pathogen cannot spread because the majority of the group are resisteant to the pathogen.  
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HYBRIDOMA   Made by combining a myeloma and a B cell.  
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IMMUNIZATION   Refers to the administration of any antigenic inoculum.  
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IMMUNODIFFUSION   These tests are precipitation reactions carried out in an agar medium.  
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IMMUNOTOXIN   A monoclonal antibody that has been combined with a toxin.  
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INACTIVATED   Microbes that have been killed by heat or chemical methods.  
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MONOCLONAL ANTIBODY   Product of a hybridoma.  
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NEUTRALIZATION   An antigen-antibody reaction in which the harmful effects of a bacterial exotoxin or virus are blocked by antibodies.  
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PRECIPITATION REACTIONS   Involve the use of IgG or IgM to form large, interlocking aggregates (lattices) with soluble antigens.  
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RECOMBINANT   Subunit vaccines that are produced by genetic engineering.  
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SEROCONVERSION   A change in a person's response to an antigen in a serological test.  
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SUBUNIT   Vaccines that only use antigenic fragments of a microorganism.  
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TITER   The concentration of serum antibody.  
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TOXOIDS   Inactivated toxins.  
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VACCINATION   Immunization.  
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VACCINE   A suspension of organisms or fractions of organisms that is used to induce immunity.  
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VARIOLATION   A crude method of vaccination using infected material from a patient.  
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WHOLE AGENT   A vaccine that uses an intact organism.  
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