exam 10
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| immunosuppressives | show 🗑
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| promoters of tolerance | show 🗑
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| show | drugs that upregulate immune system activity
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| show | drugs that work either actively or passively to infections or neoplasia
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| show | when the immune system is over active or to prevent transplant rejection
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| most common immunosuppressive drug | show 🗑
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| how do glucocorticoids work | show 🗑
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| show | non- genomic effects b/c receptor saturation. enzyme inhibition, membrane changes, calcium changes. detrimental
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| show | activates T cells by dephos TF (NFAT). increased cyto Ca. changes in gene expression. Increase in IL-2. Block T cell prolif.
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| show | blocks T cell prolif by inhibiting expression of pro-inflamm cyto and blocking action. anti cancer effects
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| how does mycophenolate work | show 🗑
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| anti-metabolites | show 🗑
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| how do anti-metabolites work | show 🗑
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| show | mimics guanine and inhibits purine syn. incorporated into DNA.
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| how does methotrexate work | show 🗑
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| show | by forming covalent bonds with cellular structures. interferes w/ DNA/RNA rep. results in apop.
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| show | ANTI-CD-52
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| show | found on all mature lymphocytes. binding induces apop, ADCC, phagocytosis, complement mediated cytosis
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| show | IL-2
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| ex of passive immune stimulant | show 🗑
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| ex of specific immune stimulant | show 🗑
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| show | mitogens (bacterial DNA). Acemannan
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| show | size (forward scatter) and granularity (side scatter)
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| show | B cells
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| CD3 is found on what cell type | show 🗑
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| show | Helper T cells
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| show | cytotoxic T cells
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| CD34 is found on what cell type | show 🗑
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