Terms from Translation unit of 04-350 at NW
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
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amino acid | show 🗑
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amino group | show 🗑
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carboxyl group | show 🗑
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variable group | show 🗑
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radical group | show 🗑
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show | the central carbon atom of an amino acid, with an amino group at one end, carboxyl group at the other and variable group
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peptide bond | show 🗑
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thymidine | show 🗑
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dihydroxyuridine | show 🗑
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inosine | show 🗑
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tRNA secondary structure | show 🗑
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show | overall 3D shape of a tRNA when stem loops are twisted and contorted. greatly influenced by rare chemically modified bases. determines which amino acyl synthetase will charge that tRNA
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anticodon | show 🗑
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show | loop of a tRNA closes to the 5' end of the molecule. Contains dihydroxyuridine
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T loop | show 🗑
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variable loop | show 🗑
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show | CCA sequence added to the 3' end of the tRNA after it has been transcribed. Serves as the connection point for the amino acid when charging occurs
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charging | show 🗑
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show | Enzyme responsible for charging the tRNA... one for each amino acid. Recognizes the tRNA with the proper shape and uses them as a substrate for the charging reaction.
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show | sequence of three nucleotides found within the mRNA that specifies which amino acid will be incorporated into the polypeptide during translation
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triplet | show 🗑
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show | one codon sequence always codes for the same amino acid
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show | a single base in a codon is part of only one codon... not multiple
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show | the genetic code is not broken up using markers to distinguish one codon from the other
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show | the genetic code has multiple codons that code for the same amino acid. also known as a degenerate code
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show | the genetic code is interpreted in the same way in nearly all organisms
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start codon | show 🗑
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stop codon | show 🗑
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show | open reading frame, a string of consecutive codons that begin with a start codon and concludes with a stop
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sense codon | show 🗑
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non Watson Crick base pairng | show 🗑
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show | improper pairing between bases at the third position of the codon and the first position of the anticodon
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show | S, unit of measure that includes not only mass but factors related to density. How likely will a molecule sink through a density gradient
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show | machinery for protein synthesis, composed of two subunits (one large and one small)
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show | complex of rRNA and protein that serves as one half of a functional ribosome
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show | complex of rRNA and protein that serves as one half of a functional ribosome
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show | amino acyl site, binding site on the ribosome where new tRNA deliver amino acids during translation
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P site | show 🗑
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show | exit site, exit channel where uncharged tRNA will leave the ribosome after being used in translation
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factor binding center | show 🗑
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show | ribozyme that is part of the large ribosomal subunit, responsible for making the peptide bonds between amino acids during translation
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show | 5' untranslated region, portion of the mRNA at the 5' end that does not contain codons, upstream of the start codon
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3' UTR | show 🗑
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show | a mRNA that contains a single ORF
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show | a mRNA that contains multiple ORF so a single RNA is responsible for multiple proteins
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ribosomal binding site | show 🗑
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initiator tRNA | show 🗑
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fMet | show 🗑
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Methionine | show 🗑
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show | initiation factor 1, in prokaryotes used to keep the A site free until the ribosome assembles
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show | initiation factor 2, protein in prokaryotes that holds the initiator tRNA in place until the ribosome assembles
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show | initiation factor 3, protein in prokaryotes that keeps lrge and small ribosomal subunits apart until they recognize a mRNA
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show | guanosine triphosphate, RNA monomer, also a high energy molecule used to drive various steps of translation
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methyl guanosine cap | show 🗑
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Kozak sequence | show 🗑
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cap binding proteins | show 🗑
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show | Elongation factor Tu, protein that guides new charged tRNA into the A site of the ribosome, carrying GTP, make contact with the factor binding center if all proper pairing of codon and anticodon occurs to stimulate peptidyl transferase
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EF-G | show 🗑
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release factor | show 🗑
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mRNA looping | show 🗑
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post translational modification | show 🗑
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Created by:
jthorns
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