clinical chem endocrinology
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| T or F? Major warning signs of adrenal disease include abnormal BP, abnormal K, acid-base, urine dilution and unexplained weight change. | true
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| The two main sites of production of heme are: | Liver and bone marrow
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| A 34 yr old women presents with goiter, tachycardia and weight loss of 2 month duration. TSH is undetectable and free T4 is high. What tests are helpful in diagnosing the cause of hypothyroidism? | TSH, TSH receptor antibodies, and RAIU
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| The two main classes of porphyrias, according to symptoms are: | Neurological and cutaneous
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| The two main sites in the body for accumulation of excess porphyrins are: | Liver and the bone marrow
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| Polarographic methods of glucose assay are based on which principle? | Rate of oxygen depletion measured
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| Serum or plasma myoglobin levels are used as: | An early marker of acute myocardial infraction
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| Inherited disorders in which a genetic defect causes abnormalities in rate and quantity of synthesis of structurally normal polypeptide chains of the hemoglobin molecules are called | thalassemias
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| Estrogen influences the secretion of which hormones? | Growth hormone, prolactin, and Luteinizing hormone
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| increased intervascular hemolysis is indicated by a decrease in: | Haptoglobin
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| Characteristics of Gierke disease: | increased plasma lactate, hypoglycemia, and subnormal response to epinephrine
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| Primary route(s) of excretion for protoporphyrin (PROTO), uroprophyrin (URO), and coproporphyrin (COPRO) are: | URO excreted primarily in urine, PROTO in the feces and CORPRO in either
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| The relationship between precursors in yhe heme synthesis pathway and the type of porphyria resulting from excess buildup of these precursors is: | excess of early precursors causes neurological porphyrias and excess of late precursors causes cutaneous porphyrias
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| The biologically most active, naturally occurring androgen is: | Dehydroepiandrosterone
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| the definitive suppression test to prove autonomous production of growth hormone is: | Oral glucose loading
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| What is responsible for epinephrine production | cortisol
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| Secondary porphyrias not due to an inherited biochemical defect in heme synthesis can be distinguished from true porphyrias by measuring levels of: | Urinary ALA and PBG
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