Hypertension
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Hypertension occurs when the BP reaches a sustained elevation of what? | show 🗑
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show | two separate readings on two separate occasions.
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What pressure is the greatest force caused by the contraction of the left ventricle? | show 🗑
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show | Diastolic BP
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show | the pressure exerted by the blood on the vessel walls
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show | *Blood flow *Peripheral vascular resistance
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show | determined by the diameter of the vessel and viscosity of the blood
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Blood flow and peripheral vascular resistance play an important role in regulating what? | show 🗑
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Increased peripheral vascular resistance results from what? | show 🗑
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show | *The sympathetic nervous system *The renin-angiotensin system of the renal system
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show | Releases epinephrine and norepinephrine that result in vasoconstriction and increased peripheral vascular resistance.
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show | Low blood flow to the kidneys.
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show | Renin
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show | Angiotensin
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show | Actual cause is unknown. Theories include: arteriolar changes, sympathetic nervous system, hormonal influence (RAAS). GENETIC FACTORS, HIGH BODY WEIGHT, SEDENTARY LIFESTYLE, INCREASED SODIUM INTAKE, EXCESSIVE ALCHOHOL INTAKE.
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Primary (essential) Hypertension constitutes what percentage of cases of hypertension? | show 🗑
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Angiotensin is released from what? | show 🗑
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show | *Age *Sex *Race *Family history
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What age is at higher risk of hypertension? | show 🗑
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True or False: African-americans are at a higher risk of hypertension than caucasian americans | show 🗑
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show | *The elastic tissue in the arterioles to be replaced by fibrous tissue. *decreased tissue perfusion resulting in deterioration of major organs.
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show | False. Its attributable to an identifiable medical diagnosis
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How does renal vascular disease affect secondary hypertension? | show 🗑
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How does primary aldosteronism affect hypertension? | show 🗑
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show | increased blood volume.
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How does Pheochromocytoma affect hypertension? | show 🗑
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Hypertension occurs when the BP reaches a sustained elevation of what? | show 🗑
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show | two separate readings on two separate occasions.
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show | Systolic BP
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What pressure occurs during the relaxation phase between heartbeats? | show 🗑
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What is arterial blood pressure is determined by? | show 🗑
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The two primary factors determining pressure exerted in the arteries | show 🗑
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What determines peripheral vascular resistance? | show 🗑
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show | Blood Pressure
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show | vasoconstriction and/or narrowing of the lumen of the peripheral blood vessel
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What controls vasoconstriction and vasodilation? | show 🗑
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How does the sympathetic nervous system affect cosoconstriction/dilation? | show 🗑
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show | Low blood flow to the kidneys.
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What leads to the formation of angiotensin? | show 🗑
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show | Angiotensin
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What causes primary (essential) hypertension? | show 🗑
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Primary (essential) Hypertension constitutes what percentage of cases of hypertension? | show 🗑
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show | The lungs
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What are the NON-modifiable risk risk factors of hypertension? | show 🗑
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What age is at higher risk of hypertension? | show 🗑
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show | True. They are at 2x greater risk.
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show | *The elastic tissue in the arterioles to be replaced by fibrous tissue. *decreased tissue perfusion resulting in deterioration of major organs.
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True or False: Like primary hypertension, secondary hypertension has no definative cause | show 🗑
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show | affects renin and sodium that results in increased vascular volume.
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show | causes sodium and water retention. excess secretion of catecholamines increases peripheral vascular resistance.
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show | increased blood volume.
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show | excess secretion of catecholamines increases peripheral vascular resistance.
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show | marked elevation of B/P in upper extremities with decrease perfusion to lower extremities.
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What is malignant hypertension? | show 🗑
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show | inflammation of the arterioles in the eyes (arteriolitis)
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Who is malignant hypertension most common in? | show 🗑
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show | Small arterioles (Most notably in major organs, heart, kidneys, brain, eyes)
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show | TRUE
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What physiological event is responsible for the most damage to organs with malignant hypertension? | show 🗑
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Hypertension is often asymptomatic until when? | show 🗑
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S/S of advanced hypertension | show 🗑
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show | Smoking
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What is Angioedema? | show 🗑
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show | Angioedema
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show | Calcium and Magnesium
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To prevent hypertension, a man of normal weight should consume no more than how much ethanol a day? What does that amount equivilate to? A woman should limit it to how much? | show 🗑
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What is the recommended sodium intake per day? | show 🗑
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What is the therapeutic goal of antihypertensive agents? | show 🗑
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How are antihypertensive drugs classified? | show 🗑
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What are some precautions to look for prior to administration of antihypertensives? | show 🗑
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What are the side effects of antihypertensives? | show 🗑
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show | Notify the physician of the clients low heart rate. Bradycardia is a side effect of beta-blockers and the drug can make it worse.
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list three things that can negate the therapeutic effects of antihypertensives | show 🗑
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What antihypertensive my cause an increase in blood glucose and a false positive for coombs? | show 🗑
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When is the last dose of the day of clonodine administered? | show 🗑
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How often should transdermal clonodine be administered? | show 🗑
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In the perioperative setting, continue clonidine up to _____ prior to surgery and resume _____ thereafter. | show 🗑
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True or False: Transdermal clonodine is the only clonodine you can use during surgury | show 🗑
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show | Weekly
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What controls arrhythmias without appearance of detrimental side effects | show 🗑
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What decreases frequency and severity of angina attacks? | show 🗑
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show | management of mild to moderate hypertension
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What is the action of adrenergics? | show 🗑
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Clonodine is a _____ | show 🗑
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show | 40% - 50%
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show | *Hypertension. *Management of symptomatic heart failure *Slowed progression of asymptomatic left ventricular dysfunction to overt heart failure
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What is the action of ACE inhibitors? | show 🗑
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show | The 'PRILs': benazepril, captopril, enalapril, fosinopril, Monopril, lisinopril, quinapril, Accupril, Moexipril, vamipril
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show | False. ALL ACE inhibitors cross the placenta.
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True or False: ACE inhibitors are commonly used with surgical procedures | show 🗑
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What increases the risk of hyperkalemia when taken with ACE inhibitors? | show 🗑
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What blunts the antihypertensive effects of ACE inhibitors when taken with them? | show 🗑
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What can increased levels/consumption of ACE inhibitors cause? | show 🗑
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show | b; Dizziness is a common initial side effect of this medication, which is usually transient. The patient should be instructed to rise from a lying position slowly to avoid orthostatic hypotension and avoid falling.
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What is the use of Angiotensin II Receptor Antagonists? | show 🗑
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What is a more preferred antihypertensive for patients with diabetes? | show 🗑
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show | blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II at various receptor sites including vascular smooth muscle and the adrenal glands. BLOCKS VASOCONSTRICTION
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show | *The 'tans' *iosartan (Cozaar). *irbesartan (Avapro). *valsartan (Diovan).
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What blunts the antihypertensive effects of Angiotetan II Receptor Antagonists when taken along side them? | show 🗑
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What increases the risk of hyperkalemia when taken with Angiotetan II Receptor Antagonists? | show 🗑
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show | *Hypertension *Angina pectoris *tachyarrhythmias *Hypertrophic subaortic stenosis *Migraine headache (prophylaxis) *MI (prevention) *Glaucoma (ophthalmic) *CHF *Hyperthyroidism.
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What is the action of Beta-blockers? | show 🗑
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show | located chiefly in the heart where stimulation results in increased heart rate, contractility, and AV conduction.
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Are beta blockers Antiarrhythmic or Antihypertensive? | show 🗑
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What are some examples of beta blockers? | show 🗑
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show | Prolongued hypoglycemia
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show | Digoxin
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Propranolol (Inderal), a beta adrenergic blocker, controls hypertension by: | show 🗑
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What are the uses of calcium channel blockers? | show 🗑
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show | inhibits the transport of calcium into myocardial and vascular smooth muscle cells, resulting in inhibition of excitation-contraction coupling and subsequent contraction.
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show | Verapamil and diltiazem
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What increases levels and effects of calcium channel blockers? | show 🗑
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What are the uses for Beta-blockers? | show 🗑
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show | Competes with adrenergic (sympathetic) neurotransmitters for adrenergic receptor sites.
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show | located chiefly in the heart where stimulation results in increased heart rate, contractility, and AV conduction.
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show | Beta-blockers are BOTH Antiarrhythmic and Antihypertensive
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show | *The 'lols' *acebutolol HCI (Sectral). *atenolol (Tenormin). *carvedilol (Coreg). *esmolol HCI (Brevibloc). *metoprolol (Lopressor).
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Beta-blockers used with insulin can cause what? | show 🗑
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Beta-blockers used with ______ can increase bradycardia | show 🗑
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show | The beta-adrenergic blocking agents block beta receptor stimulation in the heart, which then inhibits cardiac response to sympathetic nerve stimulation. This will result in a decrease in heart rate, cardiac output, and blood pressure.
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What are the uses of calcium channel blockers? | show 🗑
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show | inhibits the transport of calcium into myocardial and vascular smooth muscle cells, resulting in inhibition of excitation-contraction coupling and subsequent contraction.
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What calcium channel blockers may increase serum digoxin levels and cause toxicity? | show 🗑
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What increases levels and effects of calcium channel blockers? | show 🗑
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What is the action of aldosterone antagonists? | show 🗑
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show | bumetanide (Bumex)
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show | To prevent nocturia
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What sulfonomide (loop diuretic) controls general edema? | show 🗑
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show | *Thiazides *chloroTHIAZIDE (Diuril) and hydrochloroTHIAZIDE (Esidrix).
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a PT with a Hx of cardiac insufficiency C/O SoB. The nurse auscultates his lungs and notes bilateral crackles throughout both fields and bilateral +2 edema of lower extremities. The nurse anticipates his health care provider will prescribe ______ | show 🗑
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What is the BP range for prehypertension? | show 🗑
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show | High blood pressure damages the arteries and causes an increased resistance of the arterioles to the flow of blood
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What is a serious side effect of the vasodilator nitroprusside (Nitropress)? | show 🗑
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What is the most serious side effect of the vasodilator nesiritide (Natrecor)? | show 🗑
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Antihypertensive drug therapy for a stage 1 hypertensive African-American PT would most likely include which? (1 Vasodilators alone) (2 ACE inhibitors alone) (3 Calcium channel blockers with thiazide diuretic)(4 Beta-blockers with thiazide diuretic) | show 🗑
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