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Noninvasive Positive Pressure Ventilation

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Noninvasive Positive Pressure Ventilation   The application of positive pressure via the upper respiratory tract for the purpose of augmenting alveolar ventilation Typically administered through a nasal or oral mask Increasingly popular due to newer vents & patient interfaces  
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Goals of Noninvasive Ventilation (Acute Care)   Avoid intubation Relieve symptoms Improve gas exchange Improve patient/vent. Synchrony Maximize patient comfort Decrease length of stay  
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Indications of NPPV Acute Care   COPD Asthma Acute cardiogenic pulmonary edema Community acquired pneumonia Hypoxemic respiratory failure Immunocompromised state Do not intubate oreders Postoperative status Difficult weaning  
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Goals of Noninvasive Ventilation (Chronic care)   Improve symptoms Enhance QOL Increase survival Improve mobility  
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Indications of NPPV Chronic Care   Restrictive thoracic disease COPD Nocturnal hypoventilation  
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COPD   Studies have shown a reduction in the need for intubation of patients with acute exacerbations Reduction in in-hospital mortality Reduced length of stay NIPPV is an acceptable alternative to intubation in patients with acute exacerbation of COPD  
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Asthma   The Meduri study reported positve results in the care of 17 patients with status asthmaticus Previous authors studied suggested NIPPV was not indicated for status asthmaticus  
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Acute Cardiogenic Pulmonary Edema (a restrictive disorder)   A CPAP of 10 to 12.5 cm H20 should be considered before NPPV is used in the care of patients with acute pulmonary edema Caused by increased pulmonary capillary hydrostatic pressure pushing fluid into the interstitual space and alv.  
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Community Acquired Pneumonias   Found to be useful in only those patients with underlying COPD Current recommendations are to use NPPV on patients with community acquired pneumonias only on patients with COPD  
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Hypoxemic Respiratory Failure   Defined by PaO2/FiO2 ratio of less than 200 Studies have shown some success while others show no benefit to reduce intubations, LOS, and mortality Conflicting reports limit clinical recommendations at this time  
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Other Indications   Providing support for do-not –intubate patients Postoperative patients Difficult weans Lower nosocomial infections Use recommended for pts with mod to severe distress and immunocompromised diseases  
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Do Not Intubate   NPPV in care of do not intubate patients with irreversible disease is controversial Does offer some relief of symptoms Current recommendations is that the use of NPPV with do not intubate patients is justified if pt. Disease is reversible  
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Post Operative Patient’s   After lung resection increased PaO2 without air leaks or increasing deadspace Propholactic use after gastric bypass improved SpO2 and FVC Outcome potential looks promising  
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Difficult Weaning Patients   NPPV reduces weaning time, length of stay, incidence of VAP, and 60 day mortality Studies supported NPPV in weaning of COPD patients but cautioned in pt selection Pt. Must be cooperative, maintain airway, and clear secretions  
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Reintubations   Patients who are difficult to reintubate should not be extubated early to receive NPPV COPD patients who’s extubation failed. had improved gas exhange and reduced need for reintubation  
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Extubations   Patients who may benefit from NPPV after extubation include: COPD Acute Pulmonary Edema Post Extubation Stridor  
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Restrictive Thoracic Diseases   Includes Neuromuscular diseases, spinal cord injuries, dyphoscoliosis Provides rest to respiratory muscles Lowers PaCO2 Improves lung compliance, volume, and deadspace Pts should have symptoms of nocturnal hypoventilation before NPPV is considered  
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Long-Term care of COPD   The current recommendation is to use NPPV with pt.s having severe COPD when they exhibit Nocturnal hyupoventilation PaCO2 of 55 mm Hg or greater or PaCO2 between 50 and 54 with nocturnal desaturations  
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NPPV Criteria for Acute Respiratory Failure   Use of accessory muscles Paradoxical breathing RR > 25 b/m Dyspnea PaCO2 > 45 mmHg with pH < 7.35 PaO2/FiO2 ratio< 200  
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Exclusion Criteria for NPPV   Apnea Cardiac instability Uncooperative Facial burns Facial trauma Aspiration concerns Secretions  
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Predictors of Success in Acute Care Setting   Minimal air leak Low severity of illness PaCO2 > 45 mm Hg but < 92 mm Hg pH < 7.35 but > 7.22 Improvement within 30 minutes-2 hrs Improve RR and HR  
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Noninvasive Ventilators   Electrically powered, blower driven, and microprocessor controlled Single circuit design for constant flow Small leak is required Trigger must tolerate leak in system  
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Noninvasive Ventilators Capabilities   Provide rates to 30 b/m Pressures to 30 cm H20 EPAP to 15 cm H20 Flows of 60 l/m at 20 cm H20 pressure FiO2 to 50% Minimal re-breathing potential  
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Initial settings NPPV Ventilator   Appropriate sized interface Patient seated at 30 degree angle IPAP of 8 to 12 cm H20 EPAP of 3 to 5 cm H20 Back up rate  
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Noninvasive Ventilators Alarms   Circuit disconnect Loss of power Battery failure  
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Initial Setting Critical Care Ventilator   PSV with 5 to 8 cm H20 PEEP 0 to 5 cm H20 Flow triggering at 2 to 5 l/m  
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Initial Setting Critical Care Ventilator   A/C Mode VT of 10 ml/kg Flow of 60 l/m F of 10 b/m PEEP of 0 to 5 cm H20 Flow triggering between 2 and 5 l/m  
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Initiations of NPPV   Encourage patient to hold the mask in place while head gear is applied After pt is comfortable with initial settings, increase the inspiratory pressures or Vt until 5 to 7 ml/kg is obtained Check for leaks/adj. strap tension  
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Complications of NPPV Mask Related   Discomfort Skin erythema Claustrophobia Nasal bridge ulceration Rash  
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Complications of NPPV Flow/Pressure Related   Nasal congestion Sinus or ear pain Nasal or oral dryness Eye irritation Gastric insufflation  
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Major Complications of NPPV   Aspiration Pneumonia Hypotension Pneumothorax  
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Air Leaks   Mask fit essential Use of ExpSen% and RiseTime % to improve ventilator/pt synchrony  
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