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Advanced Higher Bio Test

Enter the letter for the matching Answer
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1.
Where does thyroid hormone bind to its receptor
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2.
After testosterone binds to its receptor in nucleus what happens next
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3.
If a person was hydrated would ADH levels go up or down
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4.
different types of cell may show a tissue specific response to the SAME signal - true or false
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5.
What is type 2 diabetes
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6.
If a person was thirsty what would the reabsorption levels be like and what effect would this have on urine
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7.
Where are receptor molecules in hydrophobic and hydrophilic signalling
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8.
Is reabsorption of water active/passive transport
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9.
When is the urine large volume but dilute
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10.
describe how insulin is transduced across a membrane (2 mark(
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11.
What is the key feature of all hydrophobic signals/ligands
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12.
what does thyroid hormone do
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13.
What happens after a receptor has a conformational change
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14.
What are the two features of a person's urine when they are thirsty
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15.
What is meant by signal transduction
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16.
WHat is the function of Glut 4 transporter
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17.
Describe how ADH is transduced across the membrane
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18.
What is type 1 diabetes
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19.
Where is ADH produced
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20.
what happens when thyroid hormone changes conformation of its receptor
A.
passive as aquaporin is a channel protein
B.
lipid soluble so can pass through membrane
C.
pituitary gland (NOT brain)
D.
in the nucleus
E.
reabsorption levels HIGH - urine small volume and concentrated
F.
down (ADH thirsty hormone)
G.
when a person is hydrated
H.
1. Insulin receptors less sensitive/Less numbers of ACTIVE receptors 2. Problems with recruiting Glut 4 to membrane
I.
ADH produced by pitituary gland in brain binds to ADH receptors in kidney tubule which change conformation resulting in a second messenger system that recruits AQP 2 to membrane to reabsorb water
J.
true
K.
activate of 2nd messenger cascase e.g. phosphorylation by kinase OR activation of Gproteins/enzymes
L.
hydrophobic (within nucleus receptors) hydrophilic (surface of cell membrane)
M.
TF inhibitor breaks away from DNA allowing transcription of Na/K ATPase
N.
increase metabolic rate by production of Na/K ATPase
O.
small volume and concentrated
P.
when then endocrine organ (pancreas) cannot produce insulin
Q.
to convert glucose into stored glycogen
R.
This changes conformation of receptor resulting in it binding to gene regulatory sequences
S.
converting an extracellular signal into an intracellular response
T.
insulin produced by pancreas, binds to receptors on liver/muscle/fat and changes conformation - recruiting glut 4 to membrane to convert glucose to glycogen
Type the Answer that corresponds to the displayed Question.
incorrect
21.
What cells are target tissues of insulin signalling
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22.
What channel protein reabsorbs water in ADH signalling
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23.
What two hormones undergo hydrophilic signalling
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24.
what is the target tissue of thyroid hormone
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25.
Give an example of a steroid hormone
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26.
What transporter is recruited to the membrane in insulin signalling
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27.
A receptor can bind any ligand
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28.
What happens after gene regulatory sequences have been activated
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29.
what is the target tissue of ADH
incorrect
30.
What is the function of ADH

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