Advanced Higher Bio Test
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| A. passive as aquaporin is a channel proteinB. lipid soluble so can pass through membraneC. pituitary gland (NOT brain)D. in the nucleusE. reabsorption levels HIGH - urine small volume and concentratedF. down (ADH thirsty hormone)G. when a person is hydratedH. 1. Insulin receptors less sensitive/Less numbers of ACTIVE receptors
2. Problems with recruiting Glut 4 to membraneI. ADH produced by pitituary gland in brain binds to ADH receptors in kidney tubule which change conformation resulting in a second messenger system that recruits AQP 2 to membrane to reabsorb waterJ. trueK. activate of 2nd messenger cascase e.g. phosphorylation by kinase OR activation of Gproteins/enzymesL. hydrophobic (within nucleus receptors)
hydrophilic (surface of cell membrane)M. TF inhibitor breaks away from DNA allowing transcription of Na/K ATPaseN. increase metabolic rate by production of Na/K ATPaseO. small volume and concentratedP. when then endocrine organ (pancreas) cannot produce insulinQ. to convert glucose into stored glycogenR. This changes conformation of receptor resulting in it binding to gene regulatory sequencesS. converting an extracellular signal into an intracellular responseT. insulin produced by pancreas, binds to receptors on liver/muscle/fat and changes conformation - recruiting glut 4 to membrane to convert glucose to glycogen |
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