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Musculoskeletal 64
Nursing management of musculoskeletal problems
Question | Answer |
---|---|
What is Osteomyelitis? | It is a severe infection of the bone, bone marrow, and surrounding soft tissue. |
Most common infecting microorganism of Osetomyelitis is? | Staphylococcus aureus |
What type of organisms cause Osteomyelitis? | Aerobic gram-negative and/or mixed with gram-positive organisms. |
What helps reduce mortality rate and complications associated with Osteomyelitis? | Use of anitbiotics in conjunction with surgical treatment. |
What are the two ways a infecting microorganisms can invade? | Indirect and direct |
What are the common sites for infection through indirect entry in children? | Distal femur, proximal tibia, humerus, and radius |
What adults are at higher risk for a primary infection through indirect entry to spread via the blood to the bone? | Adults with vascular insufficiency disorders (diabetes mellitus)and genitourinary and respiratory infection |
What are the common sites of osteomyelitis infections in adults? | Pelvis, tibia, and vertebrae |
How does direct entry of osteomyelitis occur? | At any age when there is an open wound where the microorganisms gain entry to the body. Also in the presence of a foreign body such as implant or orthopedic prosethetic device. |
What are predisposing problems of Staphylococcus aureus in osteomyelitis? | Pressure ulcer, penetrating wound, open fracture, orthopedic surgery, vascular insufficiency disorders (diabetes, atherosclerosis) |
Predisposing problems of Staphylococcus epidermis in osteomyelitis? | Indwelling prosthetic devices (joint replacements, fracture fixation devices) |
Predisposing problems of Streptococcus viridans in osteomyelitis? | Abscessed tooth, gingival disease |
Predisposing problem of Escherichia coli in osteomyelitis? | Urinary tract infection |
Predisposing problem of Mycobacterium tuberculosis in osetomyelitis? | Tuberculosis |
Predisposing problem of Neisseria gonorrhoeae in osteomyelitis? | Gonorrhea |
Predisposing problems of Pseudomonas in osteomyelitis? | Puncture wounds, IV drug use |
Predisposing problem of Salmonella in osteomyelitis? | Sickle cell disease |
Predisposing problem of Fungi, mycobacteria in osteomyelitis? | Immunocompromised host |
What is acute osteomyelitis? | Initial infection or infection of less than 1 month in duration. |
What are systemic manifestations of acute osteomyelitis? | Fever, night sweats,chills, restlessness, nausea, and malaise |
What are local manifestations of acute osteomyelitis? | constant bone pain the is not relieved by rest and worsens with activity, swelling, tenderness, and warmth at the infection site, and restricted movement of affected part. |
What are the later signs of acute osetomyelitis? | Drainage from sinus tracts to the skin and/or the fracture site. |
What is chronic osteomyelitis? | A bone infection that persists for longer than 1 month or infection that has failed to respond to initial course of antibiotic therapy. |
What are systemic signs of chronic osteomyelitis? | May be diminished. |
What are the local signs of chronic osteomylitis? | Constant bone pain and swelling, tenderness and warmth at infection site. Local signs most common. |
What is the best way to determine the causative microorganism in osteomyelitis? | Bone or soft tissue biopsy |
What diagnostic studies are used with osteomyelitis? | CBC, radiologic signs, radionuclide bone scans, MRI and CT scans. |
What is the treatment of choice for acute osteomyelitis? | Vigorous and prolonged IV antibiotic therapy as long as bone ischemia has not yet occurred. |
What is preferred to be done before treatment initiated? | Cultures or a bone biopsy. |
If antiobiotic therapy is delayed what can be done? | Surgical debridement and decompression |
Where is antibiotic therapy given? | central venous catheter or peripherally inserted centeral catheter |
What is important about gentamicin (Garamycin)? | Instruct patient to notify health care provider if any visual, hearing, or urinary problems develop. Assess patient for dehydration before starting therapy. |
What are treatments of chronic osteomyelitis? | Surgical removal, extended use of antibiotics, antibiotic-impregnated polymethylmethacrylate bead chains, irrigation with antibiotics, casts or braces, and wound VAC. |
When can hyperbaric oxygen be given in chronic osteomyelitis? | As an adjunct therapy in refractory cases of chronic osteomyelitis. |
What is done is orthopedic prosthetic device is source of chronic infection? | Must be removed |
What are long-term and mostly rare complications of osteomyelitis? | Septicemia, septic arthritis, pathologic fractures, and amyloidosis. |
What are the overall goals for patient with osteomyelitis? | 1.Have satisfactory pain and fever control 2.Not experience any complications 3.Cooperate with the treatment plan 4.Maintain a positive outlook on the outcome of the disease |
What type of meds are prescribed to provide patient comfort in patients with osteomyelitis? | NSAIDs, opioid analgesics, and muscle relaxants |
What type of dressings are used on patient with osteomyelitis? | Dry, sterile dressings; dressings saturated in saline or antibiotic solution; and wet-to-dry dressings |
What is Flexion contracture? | Is a common sequel of osteomyelitis of the lower extremity because the patient frequently positions the affected extremity in a flexed position to promote comfort. Most commonly in hip and knee. |
What can develop because of flexion contracture? | Deformities (footdrop) |
What activities should patient avoid with osteomyelitis? | Exercise and heat application stimulate spread of infection. |
What are adverse effects of aminoglycosides (tobramycin, neomycin) in treatment of osteomyelitis? | Hearing deficit, fluid retention, and neurotoxicity |
What are adverse effects of extended use of cephalosporins (cefazolin) in treatment of osteomyelitis? | Jaudice, colitis, and photosensitivity |
What is adverse effect of fluoroquinolones (ciprofloxacin [Cipro], levofloxacin [Levaquin]) in the treatment of osteomyelitis? | Tendon rupture (especially Achilles tendon) |
Lengthy antibiotic therapy can result in overgrowth of what? | Candida albicans and Clostridium difficile in genitourinary and oral cavities (especially immunosuppressed and older patients). |
Patients on lengthy antibiotic treatments for osteomyelitis should report what to health care provider? | Whitish, yellow, curdlike lesions. |
What is Osteomalacia? | It is a uncommon disease of adult bone associated with vitamin D deficiency resulting in decalcification and softening of bone. |
What are the etiologic factors in the development of osteomalacia? | Lack of exposure to ultraviolet rays, GI malabsorption, extensive burns, chronic diarrhea, pregnancy, kidney disease, and drugs such as phenytoin (Dilantin). |
What are the most common clinical features of osteomalacia? | Localized bone pain, difficulty rising from chair, and difficulty walking. |
What are other clinical manifestations of osteomalacia? | low back pain and bone pain, progressive muscular weakness (pelvic gridle), weight loss, and progressive deformities of the spine (kyphosis) or extremities. |
What is a sign of delayed bone healing in osteomalacia? | Fractures (common) |
What are common lab findings in patients with osteomalacia? | Decreased serum calcium or phosphorus levels, decreased serum 25-hydroxyvitamin D, and elevated serum alkaline phosphatase. |
What can be found in x-rays of patients with osteomalacia? | Looser's transformation zones (ribbons of decalcification in bone found on x-rays)are diagnostic of osteomalacia. |
What is prescribed in the treatment of vitamin D deficiency associated with osteomalacia? | Vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol), calcium salts and phosphorus supplements. |
What dietary intake is encouraged for treatment of osteomalacia? | Eggs, meat, oily fish, and milk, and breakfast cereals fortified with calcium and vitamin D. |
What are other things that can help with treatment of osteomalacia? | Exposure to sunlight (and ultraviolet rays) along with weight-bearing exercise. |
What is osteoporosis (fragile bone)? | Is a chronic, progressive metabolic bone disease characterized by low bone mass and structural deterioration of bone tissue, leading to increased bone fragility. |
What is osteoporosis known as and why? | "Silent thief" because it slowly and insidiously over many years robs the skeleton of its banked resources. |
Why is osteoporosis more common in women than men? | 1.Women tend to have lower calcium intake 2.Women have less bone mass 3.Bone resorption begins at an earlier age 4.Pregnancy and breastfeeding deplete reserves 5.Longevity increases likelihood |
What helps to decrease the risk of osteoporosis? | Regular weight-bearing exercise, fluoride, calcium, and vitamin D ingestion. |
What happens to the remodeling process during osteoporosis? | Bone resorption exceeds bone deposition. |
Where does osteoporosis most commonly occur? | Bones of spine, hips, and wrists. |
Wedging and fractures of vertebrae produce in osteoporosis? | Gradual loss of height and a humped back known as "dowager's hump" or kyphosis. |
What is the first signs of osteoporosis? | Back pain or spontaneous fractures |
What diseases are associated with osteoporosis? | Inflammatory bowel disease, intestinal malabsorption, kidney disease, RA, hyperthyroidism, and diabetes mellitus |
What drugs affect osteoporosis? | Corticosteroids, antiseizure drugs (divalproex sodium [Depakote], phenytoin [Dilantin]), aluminum-containing antacids, heparin, certain cancer treatments, and excessive thyroid hormones |
What does corticosteriods do in patients with osteoporosis? | Causes a loss of bone and inhibition of new bone formation. |
What are clinical manifestations of osteoporosis? | Sudden strain, bump, or fall causes a hip, vertebral or wrist fracture. Collapsed vertebrae may initially be manifested as back pain, loss of height, or spinal deformities (kyphosis). |
What is quantitative ultrasound (QUS)? | Measures bone density with sound waves in the heel, kneecap, or shin. |
What is dual-energy x-ray absorptiometry (DEXA)? | Measures bone density in the spine, hips, and forearms also to assess the effectiveness of treatment. Reported as T-scores. |
Osteoporosis is a BMD of? | Osteoporosis is defined as a BMD of <_-2.5 below the mean BMD of young adults. |
What is used to differentiate the diagnosis of osteoporosis and osteomalacia? | Bone biopsy |
The National Osteoporosis Foundation recommends treatment for osteoporosis... | For postmenopausal women who have(1)a T-score of<_-2.5(2)T-score btw-1and-2.5 w/risk factors(3)prior history of hip or vertebral fracture. |
What is FRAX? | Fracture Risk Assessment tool takes into account bone mineral density and additional clinical factors when assessing fracture risk. |
What is adequate Calcium intake? | 1000mg/day in premenopausal women and postmenopausal women taking estrogen 1500mg/day in postmenopausal women who are not receiving supplemental estrogen |
What are food high in calcium content? | Whole and skim milk, yogurt, turnip greens, cottage cheese, ice cream, sardines, and spinach. |
How much is supplemental vitamin D and who is it prescribed for? | vit D 800 to 1000IU recommended for postmenopausal women, older adults, homebound ppl, and ppl who get minimal sun exposure. |
What is weight-bearing exercises? | Its a exercise that forces a individual to work against gravity. Such as walking,hiking,weight training,stair climbing,tennis,and dancing. |
What should the patient cut down on to decrease the likelihood of losing bone mass? | Smoking and alcohol intake |
What regimen should the patient with osteoporosis follow? | Calicum and vitamin D supplementation, exercise, and medications (alendronate [Fosamax], raloxifene [Evista]). |
What is Vertebroplasty? | Bone cement is injected into the collapsed vertebra to stabilize it, but it does not correct the deformity in osteoporosis. |
What is Kyphoplasty? | An air bladder is inserted into the collapsed vertebra and inflated to regain vertebral body height and then bone cement is injected. |
Why is estrogen replacement therapy no longer given as primary treatment to prevent osteoporosis after menopause? | Increased risk of heart disease and breast and uterine cancer. |
What does estrogen do in treatment of osteoporosis? | Inhibits ostoclast activity, leading to decreased bone resorption and preventing both corical and trabecular bone loss. |
Salmon calcitonin (Calcimar) is used in treatment of osteoporosis in what forms can it be used? | IM,subQ,and intranasal forms |
Bisphosphonates are used in treatments of osteoporosis what is the names of these drugs? | etidronate (Didronel),alendronate (Fosamax), pamidronate (Aredia),risedronate (Actonel), clondronate (Bonefos), tilufronate (Skelid), and ibandronate (Boniva) |
What are common side effects of bisphosphonates in the treatment of osteoporosis? | Anorexia, weight loss, and gastritis |
What rare serious side effect is associated with bisphosphonates in treatment of osteoporosis? | Jaw osteonecrosis (occurs most frequently in patients with advanced cancer) |
What instruction should be given to patients taking bisphophonates in the treatment of osteoporosis? | Take with full glass of water,take 30 minutes before food or other medications, and to remain upright for at least 30 minutes after medications. |
Selective estrogen receptor modulator(raloxifene[Evista]) are also used in treatment of osteoporosis. What do they do? | Reduces bone resorption without stimulating the tissues of breast or uterus. |
What are side effects of raloxifene (Evista)? | Leg cramps, hot flashes, and blood clots |
How does teriparatide (Forteo) help in treatment of osteoporosis? | Increases the action of osteoblasts. First drug approved that stimulates new bone formation. |
What are side effects of teriparatide (Forteo) in treatment of osteoporosis? | Leg cramps and dizziness |
What is denosumab (Prolia) used for? | Postmenopausal women with osteoporosis who are high risk for fractures. It inhibits osteoclast formation and function. |
What is Paget's disease? | (Osteitis deformans) is a chronic skeletal bone disorder where there is excessive bone resorption followed by replacement of normal marrow by vascular, fibrous connective tissue. |
What parts of the body are usually affected by Paget's disease? | Pelvis, long bones, spine, ribs, sternum, and cranium |
What are the initial clinical manifestations of Paget's disease? | Insidious bone pain, complaints of fatigue, and progressive development of waddling gait. |
What do patients with Paget's disease complain of? | Fatigue, becoming shorter and heads becoming larger |
What can happen to patients with enlarged, thickened skulls associated with Paget's disease? | Headaches, dementia, visual deficits, and loss of hearing |
What is the most common complication of Paget's disease? | Pathologic fracture and may be first indication of disease. |
What element is increased with advanced Paget's disease? | Serum alkaline phosphatase |
Administeration of human calcitonin (Cibacalcin) does what in Paget's disease? | Bone resorption, relief of acute symptoms, and lowering the serum alkaline phosphatase levels. It inhibits osteoclastic activity. |
What drugs are used in the treatment of Paget's disease? | Human calcitonin (Cibacalcin),salmon calcitonin (Calcimar), bisphosphonate drugs, zoledronic acid (Reclast),calcium and vitamin D. |
Calcium and vitamin D are given to reduce what common side effect of drugs used to treat Paget's disease? | Hypocalcemia |
What other treatments should be given to promote comfort of Paget's disease? | Firm mattress and corset or light brace |