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Neuro69
Unit IV
Question | Answer |
---|---|
Provide support, nourishment and protection to neurons? | Glial Cells |
Are specialized cells that produce the myelin sheath of nerve fibers in the periphery? | Oligodendorcytes |
Controls ↑ cognitive function, memory retention, voluntary eye movement, voluntary and expressive speech (Broca’s area)? | Frontal Lobe |
Contains Wernike’s area, which is responsible for receptive speech and for integration of somatic, visual, and auditory data? | Temporal Lobe |
Composed of the sensory cortex, controlling and interpreting spatial information? | Parietal Lobe |
Processing sight? | Occipital Lobe |
Is concerned with emotion, aggression, feeding behavior and sexual response? | The Limbic System |
Is responsible for regulating arousal and sleep-wake transitions? | Reticular Activating System (RAS) |
The ventricles and central canal are normally filled with an average of _____ of CSF? | 135mL |
Olfactory Nerve; (anterior ventral cerebrum)? | I CN |
Otic Nerve (vision; Thalamus)? | II CN |
Oculomotor (eye movement muscles and levator palpebrae muscle)? | III CN |
Trochlear (eye movement muscle, superior oblique muscle)? | IV CN |
Trigeminal Nerve; (nose, upper/lower jaw, mastication)? | V CN |
Abducens (lateral rectus of eye)? | VI CN |
Facial (muscles of expression, cheek, taste anterior 2/3 of mouth)? | VII CN |
Vestibulocochlear (ear, equillibrium)? | VIII CN |
Glossopharyngeal (pharynx, posterior tongue/taste)? | IX CN |
Vagus (PSNS heart, lungs, GI)? | X CN |
Accessory (sternocleidomastoid and trapezius muscles)? | XI CN |
Hypoglossal (muscles of the tongue)? | XII CN |
These preganglionic cell bodies are located in spinal segments T1-L2 (Norepinephrine/Acetylcholine)? | SNS |
These preganglionic cell bodies are located in the brainstem and spinal segments S2-S4 (only acetylcholine)? | PSNS |
Anterior blood circulation of the brain? | Internal Coratid Arteries |
Posterior blood circulation of the brain? | Vertebral Arteries |
Where is CSF located? | Subarachnoid space (Between Arachnoid & Pia) |
What are the 3 meninges? | Dura, Arachnoid, & Pia mater |
Longer subarachnoid space used to obtain CSF during lumbar puncture? | 3&4 Lumbar space |
Eyes do not move together? | Disconjugate Gaze |
Fine, rapid jerking movements of the eyes? | Nystagmus |
Pupils constrict with near vision? | Accomodation |
Early sign of central herniation? | Lack of pupillary constriction |
Ptosis? | Drooping eyelid |
Is tested by having the pt identify light touch & pinprick in each of the 3 divisions of the face? | Trigeminal Nerve (V) |
Myoclonus? | Spasms of the muscles |
Slow, writhing, involuntary movements of extremities? | Athetosis |
Impairment of muscle tone? | Dystonia |
These tracts carry volitional impulses from the cortex to the cranial and peripheral nerves, respectively? | Pyramidal Tract |
Useful in assessing vasospasm associated with subarachnoid hemorrhage, altered IC blood flow? | Transcranial Doppler |
Measures metabolic activity of brain to assess cell death or damage? | Positron Emission Tomography (PET) |
Inability to recognize bodily defect or disease (Lesion Right Parietal Cortex)? | Anosognosia |
Loss or impaired language faculty (Left Cerebral Cortex Lesion)? | Aphasia/Dysphagia |
Lack of coordination in articulating speech (Cerebellar or Cranial Nerve function)? | Dysarthria |
Inability to recognize form of object touch; lesions in parietal cortex? | Astereogenosis |
Absence of muscle tone and contractility, inability to voluntarily empty; happens in early stages of spinal cord injury? | Atonic (autonomous) bladder dysfunction |
What causes a hypertonic bladder (I.e. Dribbling)? | Lesions in pyramidal tracts (efferent pathways) |
What would cause tetraplegia(quadraplegia)? | Transection or mass lesion (Cervical Region) |
States that the 3 components must remain at a relatively constant volume w/in the closed skull structure? | Monro-Kellie Doctrine |
Normal ICP ranges? | 5-15 mmHg |
How do you calculate cerebral perfusion pressure? | MAP:(2DBP+SBP/3)- ICP |
What is normal cerebral perfusion pressure? | 60-100mmHg |
Characterized by systolic HTN w/ widening pulse pressure, Bradycardia & altered respirations? | Cushing’s Triad |
Results from local disruption of the functional or morphologic integrity of cell membranes & occurs most often in gray matter? | Cytotoxic Cerebral Edema |
A buildup of fluid in the brain & is manifested by ventricular enlargement? | Hydrocephalus |
The most sensitive and reliable indicator of pt’s neuro status? | Level of Consciousness (LOC) |
A medical emergency as this is a sign of brainstem compression & impending death? | Cushing’s Triad |
Flexion of arms, wrist, & fingers w/ adduction in upper extremities; extension, internal rotation & plantar flexion? | Decorticate Posturing |
All 4 extremities in rigid extension w/ hyperpronation of forearms & plantar flexion of feet (BAD)? | Decerebrate |
S/S of increased ICP? | Change in: LOC, V/S, Eyes, Motor. HA & Vomiting not preceded by Nausea. |
Indications for ICP monitoring? | GCS <8 & abnormal CT/MRI |
What is normal range of Oxygen in the brain tissue (PbtO2)? | 20-40 mmHg (LICOX system) |
A decrease in _____ constricts cerebral vessels, increase cerebrovascular resistance & decreases CBF? | PaCO2 |
An increase in ____ relaxes smooth muscle, dilates cerebral vessels, decrease cerebrovascular resistance and increase CBF? | PaCO2 |
An osmotic diuretic & is given IV? | Mannitol (Osmitrol) 25% |
Used to Tx vasogenic edema surrounding tumors & abscesses but not recommended in the mngt of head-injured pt’s? | Dexamethasone (Decadron) |
Alpha-2 agonist, used for cont. IV sedation of intubated & mechanically ventilated pts in the ICU for up to 24hrs? | Dexamedetomidine (Precedex) |
Usual Tx for DI? | Fluids, Vasopressin (Pitressin), or Desmopressin Acetate (DDAVP) |
Death from head trauma can occur at these 3 times? | Immediately after, 2hrs after, or 3 weeks after injury. |
The 3 classic s/s of epidural hematoma? | Unconsciousness at the scene, Lucid interval, Decreased LOC |
Results from injury to the brain tissue & its blood vessels (usually venus)? | Subdural Hematoma |
Prone to cerebral atrophy & subsequent development of subdural hematoma due to an increase incidence of falls? | Chronic Alcoholics |
Increase malignant & invasive; among the most devastating of primary brain tumors? | Maningioma |
Medications to Tx cerebral edema? | Dexamethasone (Decadron), Prednisone,, Methylprednisolone (Solu-Medrol) |
A method of delivering a highly concentrated dose of radiation precisely directed at a location w/in the brain? | Seterostatic Radiosurgery |
A group of chemo drugs used to Tx brain tumors? | Nitrosoureas, (BCNU)(CCNU) |
The first oral chemo agent found to cross the blood-brain barrier? | Temozolomide(Temodar) |
The inability to understand what other people are telling you? | Sensory Receptive Dysphasia |
Develops decreased LOC & a HA w/in 48hrs of head injury? | Acute Subdural Hematoma |
The only contraindication to elevating the head 30-45 degrees post-sxg? | Sxg to posterior fossa or if Burr hole has been performed (keep flat or 10-15 degrees) |
Key s/s of meningitis? | Fever, Severe HA, N/V, nucal rigidity, photophobia |
Used to Tx encephalitis caused by HSV infection? | Acyclovir (Zevirax) & Vidarabine (Vira-A) |
A response to ischemia; series of metabolic events? | Ischemic Cascade |
Area around core area of ischemia is a border zone of decreased blood flow (Possibly Viable tissue)? | Penumbra |
A blood clot or other debris circulating in the blood? | Embolus |
Results in a narrowing of the lumen, which blocks the passage of the blood through the artery? | Thrombosis |
Is dominant for language skills in R handed persons & most L handed persons; aware of deficits? | L Hemisphere |
All communication & receptive function is lost? | Global Aphasia |
A disturbance in the muscular control of speech? | Dysarthria |
Tends to be impulsive and move quickly, safety problems, impaired judgement? | R hemisphere |
Tx of choice for pts w/ A-Fib who have had a TIA? | Warfarin (Coumadin) |
Given to pts to prevent stroke after TIA; notify dentist of mes being taken; stop 10-14 days before sxg? | Ticlopidine(Ticlid) & Clopidogrel(Plavix) |
Is as effective as Mannitol in decreasing ICP? | Dextran(HSD) |
Must be administered w/in 3-4/5 hrs of the onset of clinical signs of ischemic stroke? | tPA |
Screening test for tPA? | CT head, occult bleeding, coagulation test, head trauma. |
Can be administered up to 6hrs after the onset of ischemic stroke? | Intraarterial tPA |
Complications of SAH? | Re-bleeding before Sxg & Vasospasms |
Drugs used to Tx vasospasms r/t SAH? | Nimodipine(Nimotop) CCB |
Is a predictor of both short- and long-term outcome of stroke pts | The NIHSS |
Blindness in the same half of each visual field? | Homonymous Hemianopsia |
Results in decreased safety awareness & places the pt at increased risk for injury? | Neglect Syndrome |
Can be prevented w/ artificial tears or gel to keep the eyes moist and an eye shield (at night)? | Corneal Abrasion |
Have trouble w/ proprioception; often are impulsive, impatient & tend to deny problems r/t strokes? | R sided brain strokes |
These pts exhibit exaggerated mood swings; anger, frustration, anxious, fearful, depressed? | L sided brain stroke (Right Hemiplegia) |
Occurs when the pt overestimates personal cognitive or capabilities & energy levels? | Maladjusted Independence |
Is the usual first-line therapy for trigeminal neuralgia? | Carbamazepine(Tegretal) or Oxcarbazepine(Trileptal) |
Injection of glycerol through the foramen ovale into the trigeminal cisern? | Glycerol Rhizotomy |
Predominate trigger causes of trigeminal neuralgia pain? | Touch & tickle (Temp. changes) |
Methods for Tx Bell's Palsy? | Moist heat, gentle, electrical stimulation, & Rx exercises. |
Drug therapy for Bell's Palsy? | Acyclovir(Zovirax) & Prednisone |
The most recognized organism associated with Guilian-Barre Syndrome? | Campylobacter jejuni |
Usually develop 1-3 weeks after an upper respiratory or GI infection? | Guilian-Barre Syndrome |
Most serious complication of Guilian-Barre Syndrome? | Respiratory Failure, SIADH |
Collaborative care for GBS? | Plasmapheresis within first 2 wks & immunoglobulin(Sandoylobulin) |
Is due to the loss of vasomotor tone caused by injury; hypotension, bradycardia, decreased SNS, venous pooling (T6 or higher)? | Neurogenic Shock |
Decreased reflexes, decreased sensation and flaccid paralysis below the level of the injury? | Spinal Shock |
Most unstable of all injuries because the ligamentous structures that stabalize the spine are torn? | The Flexion-Rotation injury |
Spinal cord level; sympathetic outflow; Temp control and blood vessels? | (T1-L4) |
Level of the Phrenic Nerve? | C3-5 |
Will cause Tetraplegia? | C7 or higher |
Will cause Paraplegia? | T1 and lower |
Control upper limbs? | C5-T1 |
is a result of damage to one half of the spinal cord? | Brown-Sequard Syndrome |
May be used to Tx delayed gastric emptying; cord damage above T5 (GI)? | Metoclopramide(Reglan) |
Should be given with in 8hrs of spinal cord injury, contra with penetrating trauma? | Methylprednisone(MP) |
Side effects of Methylprednisone(MP)? | Immunosupression, increased GI bleed, Risk for infection |
Used to maintain a MAP of >90mmHg to increase perfusion of the spinal cord? | Dopamine(Intropin) |
Lesion above _____: Bradycardia, hypotension, postural hypotension absence of vasomotor tone? | T5 & Higher |
Spasms may be controlled with these antispasmotic drugs? | Baclofen(Lioresal), Dantrolene)Dantrium), Tizanidine(Zanaflex) |
These injections may be given to Tx severe spasticity? | Botulism Toxin Injection |
A massive uncompensated cardiovascular reaction mediated by SNS; life threatening emergency? | Autonomic Dysreflexia |
Nursing interventions for autonomic dysreflexia? | HOB 45, notify MD, Assess cause (bladder or bowel) |
Arteriolar vasodilator used to Tx autonomic dysreflexia? | Nifedipine(Procardia); decreased BP |
S/S of autonomic Dysreflexia? | Sudden Acute HA, increased BP, decreased HR, Facial Flushing diaphoresis. |
Lack of coordination between detrusor contraction and urethral relaxation? | Dyssynergia |
Have become the first line therapy for acute migraine attack? | Triptans(Sumatriptan[Imitrex]) |
These drugs cause constriction of coronary arteries? | Triptans |
Excess dose of Triptans may produce these s/s? | Tremors and decreased RR |
This antiseizure drug has been shown to prevent migraine HA? | Topiramate(Topamax), and Divalproex(Depakote) |
A type of nonfluent aphasia; damage to the frontal lobe; understands speech? | Broca's Aphasia |
A type of fluent aphasia; damage to temporal lobe; difficulty understanding others? | Wernicke's Aphasia |
Medication used to Tx hiccups & shivering?# | Chlorpromazine(Thorazine); antipsychotic. |
What are the phases of progression of a seizure? | Prodromal, Aural, Ictal, and Postictal phase. |
Stiffening of the body? | Tonic Phase |
Jerking of the extremities? | Clonic Phase |
Is a brief staring spell that lasts only a few seconds, so it often occurs unnoticed? | Absence Seizure (Petit-Mal) |
Anticipated medications for seizures? | Phenytoin(Dilantin), Ativan, Valium or Versed. |
Seizure drugs? | Tegretol, & Phenobarbital |
Used as an adjunct to medications when Sxg is not feasible? | Vagal Nerve Stimulation |
Trauma changes the Fxn of the axon, resulting in swelling & disconnection. Clinical s/s ↓LOC, ↑ICP, decortication and decerebration & Global aphasia? | Diffuse Axonal Injury (DAI) |