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NPN & PLASMA PROTEIN
Question | Answer |
---|---|
What are the NPN compounds? | Urea, Creatinine, Uric Acid, Ammonia, Creatine, Amino Acids |
What is urea the breakdown product of? | Protein |
What does BUN stand for? | Blood Urea Nitrogen -- waste product down |
What 2 things affect serum BUN? | A. Protein in diet B. Urine Volume BUN = 7-20mg/dL |
What causes increased BUN? | A. Pre-renal 1. Dehydration B. Renal cause C. Post renal |
What is azotemia? | Increase of NPN's in blood Acidosis, water & electrolyte. Inbalance, coma and death. |
What does creatine and phosphocreatine break down into? | Creatinine - waste product |
What are two tests to assess kidney function? | Bun , creatinine |
What is uric acid the break down product of ? | Nucleic Acids |
Which foods are high in purines? High protein foods. | Meat |
When is uric acid increased in the serum? | Gout |
Where is ammonia made? | Made by bacteria in intestine |
What are amino acids? | Building blocks of Protein |
What is the function of each of the following protein fractions? | A. Albunin - Maintain normal blood volume B. Fibrinogen - necessary for clotting C. Gamma globulins - antibodies |
What does TSP stand for? | Total Serum Protein |
What is a normal A/G ratio decreased? | 1.0 - 2.5 |
What is electrophoresis? | specific fractions |
What is an important function of proteins? | Transport of metals, hormones, lipids. |