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MedSurge-Cancer
Question | Answer |
---|---|
Cancer S/S | CAUTION C change in bowel/bladder A a sore that won't heal U unusual bleeding/discharge T thickening lump I indigestion/difficulty swallowing O obvious change wart/mole N nagging cough/hoarseness |
Genetic tests (BRCA1, BRCA2) | mutations in genes can dispose woman to high risk of breast cancer |
Tissue Biopsy | definitive diagnosis of abnormal cells |
CBC and differential | screening for leukemia's |
Chest X-ray, CT scan, MRI, PET, SPECT | used to visualize tumors, metastasis, or progression of cancer |
CEA, CA-125, PSA, beta-hG, AFP | blood tests that screen for cancers of colon, pancreas, liver, prostate, uterus, and ovaries |
CEA, acronym for? | carcinoembryonic antigen |
CA-125, acronym for? | cancer antigen 125 |
PSA, acronym for? | prostate-specific antigen |
beta-hCG, acronym for? | human chronic gonadotropin |
AFP, acronym for? | alpha fetoprotein |
Tumors are staged based on? | tumor, node, metastasis |
Staging Tumor (TX) | unable to evaluate the primary tumor |
Staging Tumor (T0) | no evidence of primary tumor |
Staging Tumor (Tis) | tumor in situ |
Staging Tumor (T1, T2, T3, or T4) | size and extent of tumor |
Staging Tumor (NX) | unable to evaluate regional lymph nodes |
Staging Tumor (N0) | no evidence of regional node involvement |
Staging Tumor (N1, N2, N3, or N4) | number of nodes that are involved and/or extent of spread |
Staging Tumor (MX) | unable to evaluate distant metastasis |
Staging Tumor (M0) | no evidence of metastasis |
Staging Tumor (MI) | presence of distant metastasis |
SIADH, acronym for? | Syndrome of Inappropriate Diuretic Hormone |
SIADH, causes? | water retention, dilution of electrolytes (sodium) |
SIADH, nursing response... | - monitor for hyponatremia - admin. Furosemide - admin. HYPERtonic saline |
define epistaxis | nosebleed |
Place cancer pt. in private room if WBC count less than? | 1,000/mm3 & initiate neutropenic precautions |
Neutropenic Precautions... | - mask pt. during transport - pt. remain in room - clean room, H2O, no plants - restrict ill visitors - avoid invasive procedures/needles - keep equip. in pt. room - admin. Colony-stimulating factors |
Colony-stimulation factor meds? | eg. Neupogen, Neulasta |
Cancer pt. should wash toothbrush in? | dishwasher or rinse in bleach solution |
Megesterol (Megace) is administered to? | increase pt. appetite |
Mouth care should be done (before / after) meals? | before to enhance client's appetite |
Antiemetics should be administered? (before / after meals)? | before |
Improvement in metallic taste can be accomplished by? | - using plastic utensils - sucking hard candy - avoiding red meats |
For itchy scalp associated with alopecia, pt. can use | diaper rash ointment |
____-based mouth washes should be avoided with mucositis | Glycerin |
Pt. should rinse mouth with what solution? | 0.9% NaCL and half peroxide, BID w/soft toothbrush |
Cancer diet considerations? | soft foods, high proteins eg. mashed potatoes, scrambled eggs, cooked cereals, milk shakes, ice cream, yogurt, bananas |
Bleeding precautions... | - avoid IV's / injections - apply pressure @10 min. - handle pt. gently, avoid trauma |
S/S Anemia | - fatigue - pallor - dizziness - SOB |
Anemia med to administer... | Erythropoietin Alfa (Epogen) |
Antianemic med to administer... | Ferrous sulfate (Feosol) |
S/S Thrombocytopenia | - petechiae - ecchymosis - bleeding gums - nosebleeds - blood in stools, urine, vomitus |
Thrombopoietic med to administer... | Oprelvekin (Interleukin 11, Neumega) |
Platelets should be administered if count falls below? | 30,000/mm3 |
define Brachytherapy | radiation administered internally with an implant |
IV radiation drug? | radionuclide iodine |
Dosimeter film badge is used to? | records the amount of radiation exposure |
When pt. is receiving brachytherapy, visitors should? | - limit visit to 30 min. - remain 6ft. from pt. - should not be pregnant - should be over 16 yrs. |
A common side effect of radiation therapy is? | fatigue |
Effective meds against tumors that require hormone support? | Leuprolide (Eligard, Lupron) |
Androgenic hormones can suppress cancer in pts. with? | estrogen-dependent cancer |
Estrogenic hormones can suppress cancer in pts. with? | testosterone-dependent cancer |
Males receiving Estrogenic hormones may experience? | gynectomastia, hot flashes, bone loss |
Flutamide (Eulexin) is a? | Androgen antagonist |
Estrogen antagonists S/E? | N/V, hot flashes, weight gain, vaginal bleeding, inc. risk thrombosis |
The two primary cytokines used in immunotherapy are? | Interleukins and Interferons |
Interlulkins... | help coordinate the inflammatory and immune responses of the body (lymphocytes) |
Interferons... | when stimulated, can exert an anti-tumor effect by activating a variety of responses |
Cytokines... | work to enhance the immune system |
Interleukin's, monitor for? | flu-like symptoms, edema |
Interferon's, monitor for? | peripheral neuropathy (issues w/vision, hearing, balance, gait) |
Progression is the? | Final stage of cancer |
Progression is characterized by | - increased growth rate - increased invasiveness - spread of the cancer to a distant site |
Progression occurs due to? | - rapid proliferation - decreased cell adhesion - production of metalloproteinase enzymes |
Tumor-associated antigens | the altered cell surface antigens as a result of malignant transformation |
3 Methods of cancer pain management? | surgery / radiation / chemotherapy |
Opioids in cancer Tx, given for? | moderate to severe pain |
Antidepressants in cancer Tx, given for? | to reduce associated depression, promote sleep, and increase serotonin levels that may improve feelings of well-being |
Anticonvulsants in cancer Tx, given for? | to treat neuralgia or neuropathic-type pain |
Steroids in cancer Tx, given for? | reduce pain by reducing swelling |
Adjunctive agents (Sympatholytic agents) in cancer Tx, given for? | Used to treat neuropathic pain |
Skeletal muscle relaxants in cancer Tx, given for? | May be used along with other pain meds for muscle spasms assoc. with cancer pain |
Rectal med administration, contraindicated in pts. with? | low WBC or low platelet count |
Anesthetic used for isolated pain? | bupivacaine and/or a corticosteroid |
Intercostal nerve blocks used for? | anesthetic for chest or abdominal wall pain, procedure 15 min - 1 hr. |
S/S Systemic Infusion... | metallic taste, ringing in ears, perioral numbness, seizures |
Location of epidural space _____ | space outside the dura mater of the spinal cord |
Location of intrathecal space _____ | the subarachnoid area within the spinal cord sheath that contains cerebrospinal fluid |
External catheter placed for long-term pain management of which areas? | abdomen, thorax, below umbilicus |
Neurolytic ablation, involves? | interrupting the nerve pathway or destroying the nerve roots that are causing pain |
Neurolytic ablation may cause... | loss of sensory, motor, and autonomic function |
Radiofrequency ablation, involves? | Electrical currency creates heat on a probe guided to tumor or nerves; to destroy cancer cells or ablate nerve endings |
Cryoanalgesia, involves? | Uses a needle-like probe to deliver extreme cold to interfere with pain conduction via nerve pathways |
Transcutaneous electrical nerve stimulation, (TENS) involve? | Low-volt electrical impulses transmitted thru electrodes attached to the skin |
Do not use TENS on pts. with? | pacemakers or infusion pumps |
metastasis is? | cancer cells may invade surrounding tissues and/or spread to other areas of the body |
Carcinomas arise from? | epithelial tissue |
Adenocarcinomas arise from? | glandular organs |
Sarcomas arise from? | mesenchymal tissue |
Leukemias are? | malignancies of the blood-forming cells |
Lymphomas arise from? | lymph tissue |
Multiple myeloma arises from? | plasma cells and affects the bone |