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MedSurge-CAD
MedSurge CORONARY ARTERY DISEASE review
Question | Answer |
---|---|
Three stages of CAD lesions usually present and age? | 15 - fatty streak; 30 - raised fibrous plaque; >30 - complicated lesion |
Non-modifiable risk factors for CAD? | age, sex (males higher), hereditary (african american's highest; asian's lowest) |
Pt. teaching for female with risks of CAD? | CAD leading cause of death in women, higher mortality rate following MI than men |
Most of the triglycerides are contained in? | VLDL (very-low-density lipoproteins) |
Most cholesterol is contained in? | LDL (low-density lipoproteins) |
The higher the level of _____, the lower the risk of CAD? | HDL (high-density lipoproteins) |
HDL's carry lipids away from _____ to the _____. | arteries; liver |
Increases in _____ are associated with obesity? | VLDL (very-low-density lipoproteins) |
High levels of _____ correlate most closely with CAD? | LDL (low-density lipoproteins) |
Therapeutic Lifestyle Changes diet recommendations emphasizes a reduction in? | red meats, whole-milk products, eggs (alcohol and simple sugars - if triglycerides are high) |
Diet therapy is indicated for? | pts. without CAD; 2+ risk factors; LDL ≥ 130 mg/dL |
Drug therapy is added to Diet therapy when? | pts. LDL ≥ 160 mg/dL |
A temporary and reversible MI is called? | stable angina |
Myocardial ischemia occurs as a result of? | ↑ O2 demand / ↓ O2 supply |
Prinzmetal's angina results in? | ↓ O2 supply |
Prinzmetal’s (Variant) angina almost always occurs? | when a person is at rest, usually between midnight and early morning (in response to coronary artery spasms) |
Triggers for Prinzmetal’s angina include? | exposure to cold, emotional stress, smoking, cocaine use, or meds that cause the heart’s coronary arteries to narrow |
Unstable angina is characterized by? | being unpredictable, unrelieved at rest, progressive severity |
Angina decubitus occurs when the person is in which position? | recumbent |
Chronic stable angina is characterized by? | usually precipitated by exertion, occurs with same pattern of onset, duration, intensity |
Drug class to promote - decreased preload | nitrates |
Drug class to promote - dilation coronary arteries | nitrates, calcium channel blockers |
Drug class to - prevent thrombosis of plaques | anti-platelet aggregation agents (incl. aspirin) |
Drug class to promote - ↓ HR | calcium channel blockers, b-adrenergic blocking agents |
Drug class to promote - ↓ afterload | nitrates, b-adrenergic blocking agents |
Drug class to promote - ↓ myocardial contractility | calcium channel blockers, b-adrenergic blocking agents |
In healing of myocardium after an infarct, early scar tissue results in an unstable heart wall for a period of? | 4 to 10 days |
NSTEMI is more frequently treated initially with? | acute intensive drug therapy |
Increased BNP would be an indication of? | chronic heart failure |
Increased CPK-MB would be an indication of? | a myocardial infarction |
A positive D-dimer would be indication of? | a pulmonary embolus |
A positive ventilation-perfusion (V/Q) scan, would be an indication of? | a pulmonary embolus |
Cardiac Enzymes - CPK-MB elevates within? | 12 to 24 hrs |
Cardiac Enzymes - LDH elevated within? | 24 to 36 hrs |
Cardiac Enzymes - Troponin elevates within | 1 to 2 hrs |
Pyrosis is? | belching |
Mid-epigastic pain and pyrosis are indication of? | Peptic ulcer disease |
A pt. with CAD should perform _____ exercises; to increase muscle tone | isotonic |
A typical early manifestation of mitral valve stenosis is? | dyspnea on exertion |
Traits of Type A personality include: | individual often suppresses anger and hostility, has sense of time urgency, is impatient, often creates stress and tension |
Traits of Type B personality include: | more asygoing, takes upsets in stride, knows personal limitations, takes time to relax, not an overachiever |
Homocysteine is produced by? | the breakdown of the essential amino acid methionine, found in dietary protein |
CAD can be indicated by a _____ level of Homocysteine in the blood | increased |
Examples of fruits packed with complex carbohydrates? | apricots, oranges, plums, pears, grapefruits and prunes |
Examples of vegetables packed with complex carbohydrates? | broccoli, cauliflower, spinach, turnip greens, eggplant, potatoes, yams, corn, carrots, onions |
HMG-CoA Reductase Inhibitors (Statins) mechanism of action? | block synthesis of cholesterol and increase LDL receptors in liver |
Niacin mechanism of action? | inhibits synthesis and secretion of VLDL and LDL |
Fibric Acid Derivatives mechanism of action? | ↓ hepatic synthesis and secretion of VLDL; ↓ triglycerides by ↓ VLDL |
Bile-Acid Sequestrants mechanism of action? | bind with bile acids in intestine, forming insoluble complex and excreted in feces |
Cholesterol Absorption Inhibitors mechanism of action? | inhibits the intestinal absorption of cholesterol |
S/S of rhabdomyolysis include? | ↑ creatine kinase levels, muscle tenderness |
Once a woman reaches menopause, her risk for MI? | quadruples |