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Ch.110 Bio Weapons
Pharmacology for Nurses
Question | Answer |
---|---|
Bacillus Anthracis (Anthrax): Caused by the Bacillus anthracis ________ | bacterica |
Bacillus Anthracis (Anthrax): can be transmitted through ________, _________, or ____ exposure | inhalation, cutaneous, GI |
Bacillus Anthracis (Anthrax): Spores can remain ____ and survive ____ environments until enter a host and becomes an active bacteria | dormant; harsh |
Bacillus Anthracis (Anthrax): Anthrax is ____ transmitted person-to-person | NOT |
Bacillus Anthracis (Anthrax):inhalation- latency can last from ___day to ___ weeks in regional lymph nodes | 2 ;6 |
Bacillus Anthracis (Anthrax):inhalation- Bacilli release ____ causing hemorrhage, edema, and necrosis | toxins |
Bacillus Anthracis (Anthrax):inhalation- initial symptoms include ____, ____, malaise, and weakness | fever, cough |
Bacillus Anthracis (Anthrax):inhalation- 2-3 days later a sudden increase in ____, ____ distress, septicemia, hemorrhage meningitis, and ____ may occur | fever; respiratory; shock |
Bacillus Anthracis (Anthrax):cutaneous- symptoms being ___-___ days after exposure to spores | 1-7 |
Bacillus Anthracis (Anthrax):cutaneous- small ____ or vesicle develops with localized ____ | papules; itching |
Bacillus Anthracis (Anthrax):cutaneous- lesion enlarges and causes painless____ with ____ core | ulcers; necrotic |
Bacillus Anthracis (Anthrax):cutaneous- lesion develop ____ and sloughs off within 12-14 days | eschar |
Bacillus Anthracis (Anthrax):cutaneous- systemic ____ may develop and is deadly and rare | infection |
Bacillus Anthracis (Anthrax):TREATMENT- ____ treated with IV ciprofloxacin, doxycycline | Inhalation |
Bacillus Anthracis (Anthrax):TREATMENT- ____ treated with PO cipro/ doxy | Cutaneous |
Bacillus Anthracis (Anthrax): vaccination pre-exposure includes ____ with three subQ injections given 2 weeks apart | BioThrax |
Bacillus Anthracis (Anthrax):Vaccine- common side effects include muscle/joint aches, headache, local redness/tenderness, fatigue, and ____ | nausea |
Bacillus Anthracis (Anthrax): People at high rick of exposure and those dealing with ____ from anthrax-endemic areas | animal products |
Bacillus Anthracis (Anthrax): Post-exposure prophylaxis includes ____ plus ____ | antibiotic; vaccination |
Yersinia Pestis (Pneumonic Plague: caused be gram-____ bacillus Yersinia pestis | negative |
Yersinia Pestis (Pneumonic Plague): can be ____ with tender, enlarged, inflamed lymph nodes or ____ with inflammation of lungs | bubonic; pneumonic |
Yersinia Pestis (Pneumonic Plague): _____ caused be bite of flea and is not transmitted person-to-person | Bubonic |
Yersinia Pestis (Pneumonic Plague): ____ plague can be spread by coughing and fatality rate is high | Pneumonic |
Yersinia Pestis (Pneumonic Plague): Occurs 2-4 days after exposure; high ____, ____, ____, hemoptysis, GI upset, respiratory failure -> death | fever, shortness of breath, cough |
Yersinia Pestis (Pneumonic Plague): Treatment includes ____ streptomycin, IM or __ gent, or doxy, cipro | IM; IV |
Yersinia Pestis (Pneumonic Plague): No ____ to protect against disease | vaccine |
Variola Virus (Smallpox): very _____ and deadly | contagious |
Variola Virus (Smallpox): human are the ____ natural reservoir for the virus | ONLY |
Variola Virus (Smallpox): no ____ exists, but ____ is key | cure; prevention |
Variola Virus (Smallpox): virus enters through ____ membranes by inhalation | mucus |
Variola Virus (Smallpox): Incubation is 12-14 days followed by prodromal phase mainfestion with high ___, ___, prostration, headache, and backache | fever; malasis |
Variola Virus (Smallpox): small red spots develop on tongue, then bursting causing large eruptions of ____ into the mouth and throat | virus |
Variola Virus (Smallpox): skin eruptions occur with the samae ____ rash, then pus-filled rashes that form crust then scab and then scab falls off leaving pitting ____ | vesicular; scar |
Variola Virus (Smallpox): ____ mortality rate with smallpox | 30% |
Variola Virus (Smallpox): transmission occurs person-to-person by ____ or ____, contact with ____ or ____ | touch; inhalation; bedding; clothing |
Variola Virus (Smallpox): person remains ____ until scab fall off completely | infectious |
Variola Virus (Smallpox): vaccination is not currently recommended for general public, but for select ____ | population |
Botulinum Toxin: produced by Clostridium botulinum and is the most ____ poison known | potent |
Botulinum Toxin: acts by ____ nerve transmission at neuromuscular junction | blocking |
Botulinum Toxin: descending flaccid ____ beginning 12-72 hours after exposure; double vision, blurred vision, drooping eyelids, dry mouth, difficulty speaking/swallowing, and muscle weakness; starts with shoulder then feet | paralysis |
Botulinum Toxin:Death caused by paralysis of ___ muslces | respiratory |
Botulinum Toxin: Treatment is ____ with infusion of botulism immune globulin | supported |
Chemical Weapons: Sulfur Mustard (Mustard Gas): Exists as an ____ liquid that could be released into water supplies or vaporied into the air | oily |
Chemical Weapons: Sulfur Mustard (Mustard Gas): Takes around 2-24 hours to develop after exposure; SKIN- pain, redness, swelling, blisters in warm,moist areas; EYES-caused irritation, swelling and tearing with severe exposure causing ___ | blindness |
Chemical Weapons: Sulfur Mustard (Mustard Gas): Respriratory- causes runny nose, sneezing, hoarseness, sinus pain, and dry cough with severe exposure causing ____ and ___ of lung tissue | hemorrhage and necrosis |
Chemical Weapons: Sulfur Mustard (Mustard Gas): GI can cause nausea, _____, and diarrhea and abdominal pain | vomiting |
Chemical Weapons: Sulfur Mustard (Mustard Gas): Bone marrow- can cause bone marrow suppression in very high doses resulting in ____ and ____ | neutropenia; thromboytopenia |
Chemical Weapons: Sulfur Mustard (Mustard Gas): treatment includes decontamination and ____ care | supportive |
Radiation Emergencies: exposure to radiaoactive substances can cause major damage to ____ gland and increase the risk of developing ____ cancer | thyroid; thyroid |
_____ _____ can be administered to block the uptake of radioactive iodine by the thyroid | potassium iodine |
KI must be taken within ___ hours after exposure | 48 |