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PFT 02
Diffusion Capacity
| Question | Answer |
|---|---|
| definition of Diffusion | the process by which oxygen and CO2 transfer across the AC membrane |
| properties gas must have to measure diffusing capacity | -capable of diffusing across AC membrane - capable of being transported by hemoglobin - only o2 and CO could possible be considered - O2 can't be used because it varies as blood flows past alveolus |
| Diffintion of end tidal sampling | sampling of exhaled air late in the subject's expiration. |
| Contraindications | mental confusion, lack of muscle coordination, large meal before test, exercise, smoking, communicable disease |
| Things that will influence test | heavy meals, smoking, body position, hemoglobin level, exercise, bronchodilator |
| What do most equipment use for gas mixture | .3% CO, 10% Helium, balance air |
| Our equipment use for gas mixture | .3% CO, 3 % CH4, (methane), 21% O2, Balance N2 |
| How is carbon monoxide diffusion test recorded as | mlCO/min/mmhg STPD |
| Factors that influence DLCO | age (lowers), height (lowers with shortness), gender (lower in woman), ethnicity (lower in African americans by about .96 ml), Hb (lower Hb=lower DLCO) |
| equipment needed for testing | inspired gas source, 5 way breathing valve, end tidal gas sampling (analyzer), monitoriing system to record inspired and expired volume |
| Procedure | Turn on all gas tanks, anaylyzer and computers. It takes 30 min for gas pump to warm up., calibrate with spirometer, pt breaths normally, pt exhale completely (raise finger when done), pt inhale completely and hold breath until complete (11 seconds) |
| How much of exhaled volume is discarded | 1000 ml (at east 750 ml) |
| Results are reported at | STPD |
| How many tests do you perform | at least 2 but no more than 5 |
| How many times do you calibrate | daily or 2 x a day |
| What does silica gel do | absorbs moisture |
| Normal predicted | 80-120% |
| Indications for DLCO | asthma vs emphysema, follow up of emphysema, disability, effects of chemo or other drugs |
| Hemoglobin binds | 210 x faster |
| What is mormal diffusion | 25ml/min/mmhg STPD |
| What can cause decrease DLCO | O2 toxicity, emphysema |
| What can cause increase DLCO | polycythemia, LEft heart failure, high altitudes, excercise |
Created by:
TnJFarrington12
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