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NUR 100 Bio/Environm
Question | Answer |
---|---|
the immune system | body's major defense mechanism against infections, abnormal & damaged cells, bacteria, fungi, viruses & parasites |
immune system consists of | complex networks of specialized tissues, cells and organs |
immune system's goal | protect body by seeking & destroying damaged cells but preserving host |
immune system is activated by | minor and major injuries, allergic reactions |
1st phase of innate response | vascular |
2nd phase of innate response | cellular |
adaptive immune responses | cell mediated and antibody |
leukocytes | WBC's-released from bone marrow |
leukopenia | decreased # of WBC count |
leukocytosis | increased # of WBC count |
granulocytes | neutrophils, eosinophils, basophils |
monocytes, macrophages, dendritic cells | mediators of immunity, recognize foreign matters & initiate immune response |
lymphocytes | regulator of specific immune responses-t cells, B cells, NK cells |
antigens | invaders, provoke specific immune response |
antibodies | bind with antigens to deactivate them |
5 types of antibodies | IgG, IgA, IgM, IgD, IgE |
lymph | via lymph nodes |
T cells | become mature in thymus gland |
B cells | become mature in bone marrow |
T lympocytes | mature into Helper T cells, cytotoxic T cells, or memory cells |
cell mediated immune response | lymphocytes make Helper T cells, cytotoxic T cells & NK cells to deactivate the antigen |
innate immune response | 1st line of defense, nonspecific |
vascular response | state 1 of innate response. blood vessels constrict then capillary arterioles allow fluid flow, swelling, drainage |
vascular response aids in | invading bacteria gets trapped in fibrin threads |
phagocytosis | cells eating other cells |
debridement | removal of dead tissue to promote healing |
reconstruction | cells repair themselves |
adaptive immune response | at initial exposure to antigen, body develops memory and plan against specific antigen |
antibody mediated | driven by B cells which contact antigen and create antibody producing plasma and memory cells |
immunoglobulin | antibody Ig-bind and inactivate specific antigens |
B cells + antigen | antibody producing plasma cells and memory cells |
cell mediated | for sleeper cells that are hidden, initiated by T cells, cell mediated has memory, additional exposures are treated more effectively and quickly |
types of cell mediated | killer T cells and Helper T cells |
active immunity | body produces antibodies against specific antigens, naturally or artificially obtained |
passive immunity | short term, mother to baby |
natural immunity | obtained by infection resulting in antibodies |
artificial immunity | obtained by immunizations |
diagnostics | serum protein, protein electrophoresis, antibody testing, skin testing |
vaccination | suspensions of bacteria or viruses, nonpathogenic |
microorganisms | bacteria, viruses, fungi, parasites |
virulent | microorganism's ability to cause disease |
pathogens | virulent organisms rarely found in absence of disease |
infections occur when | pathogen is able to multiply within the host |
initial stage | incubation period, pathogen begins replication |
prodromal stage | manifestations appear-symptoms |
acute stage | pathogen proliferate and disseminate rapidly, byproducts released |
convalescent stage | infection contained and pathogen is eliminated |
nosocomial infection | infection obtained in healthcare setting |
white blood cell count | WBC's |
standard isolation | hand washing, gloves-treat everyone as if infected |
contact isolation | hand washing, gloves, gown-anything touchable and transferrable to other pts |
droplet isolation | hand washing, gloves, mask, gown, goggles-protect you as well as other patients and infected patient |
airborne isolation | hand washing, gloves, gown, goggles, negative air flow room, N95 mask |