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Neuroanatomy
Question | Answer |
---|---|
Central NS | Brain and Spinal Cord |
Peripheral NS | 12 cranial nerves. 31 spinal nerves. Afferent division. Efferent division. |
Afferent | Sensory |
Efferent | Motor |
Somatic | Pertaining to the body. Sensory information communicated through spinal cord. |
Visceral | Surrounding |
Ganglia | Neuron |
Dendrite | Carries impulses from synapse to cell. |
Axon | Carries electrical signals away from the cell. Cyatic nerve has largest axon. Axons are shorter in the upper body. Very sensitive to acidosis. |
Astrocytes | #1 tumor because of cell structure. Form blood brain barrier. |
Microglia | Pac Man of brain. Sensitive to acid/base imbalance. In imbalance start eating good cells. Need to keep controlled. |
Oligodenrocyes/Oligodendroglia | Support of cell. Mylen sheath. Message sending ability. Don't like exposure to viral infection, will permanently alter oligis. Viral menengitis, |
MS | rejects new mylen sheath. |
Ependyma | Line the ventricles (tanks that hold CSF) Allow for movement, progression in brain. Single layer cells of cells also on spinal cord. |
Neurotransmitters | Acetylcholine, Dopamine, Norepinephrine, Seratonin, GABA, Aspartate, Glutamic, Glycine |
Acetylcholine | Main neurotransmitter, making motor/movement. Defecit - Alzheimers, parkinsons, speech blockage. |
Dopamine | Think psych. turn off of message sending. Increased dop. - ticks. |
Norepi | Neurotransmitter of most of sypathetic NS, released from adreanal medula. Increased - anxious. |
Seratonin | Increased - sedation. Decreased - depression. |
GABA | Acid. Natural valium. Increased - coma. Decreased - Anxiety. Very fickle - likes acid/base balance. Hung up on K+ |
Aspartate | Acid. Excitatory. Changes memory. |
Glutamic | Excitatory. H2O 'hog'. Too much makes brain swell. |
Glycine | Excitatory in brain, Inhibatory everywhere else. |
Neuro Peptides | Somatostatin, Endorphins, Substance P, Histamine |
Somatostatin | Protects growth hormone. Possible cause of Alzheimers when it runs out. Needs to cross blood brain barrier. |
Endorphins | Analgesia effect. High endorphin response causes seizures, too much stress. |
Substance P | Excitable. Tendency to aggrivate microglia - panic. Controlled with acid/base balance. Prevent cascade if gotten under control. |
Histamine | Alertness. regulated by fluid onboard. (antihistamine with cold med. - get sleepy). Body makes as you need it. Goes out of control in trauma. |
Hormones | ACTH, ADH, Leptin, Ghrelin, PYY |
ACTH | Hypothalamus - production of adreanal or corticosteroid/glucocorticoid - too much sugar - acid. Anterior pituitary. |
ADH | Absorption. Fluid excretion. Released from anterior pit, sythesized in hypothalamus. |
Leptin | Appetite stimulant (in chocolate). Causes decrease in dopamine. (Parkinson's pts don't eat chocolate). |
Ghrelin | Increase hunger, decrease fat utilization. From kidney, placenta, hypothalamus. Stomach stimulates, by pass pts. loss this part of the stomach. |
PYY | Tells stomach that it is full. Hypothalamus. |