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Lilley Chapter 2
Pharm
Question | Answer |
---|---|
Additive effects | Drug interactions in which the effect of a combination of two or more drugs with similar actions is equivalent to the sum of the individual effects of the same drugs given alone. 1+1=2 |
Adverse drug event | Any undesirable occurrence related to administering or failing to administer a prescribed medication. |
Adverse drug reaction | Any unexpected, unintended, undesired, or excessive response to a medication given at therapeutic dosages. |
Adverse effects | A general term for any undesirable effects that are a direct response to one or more drugs. |
Agonist | A drug that binds to and stimulates the activity of one or more receptors in the body. |
Allergic reaction | An immunologic hypersensitivity reaction resulting from the unusual sensitivity of a patient to a particular medication; a type of adverse drug event |
Antagonist | A drug that binds to and inhibits the activity of one or more receptors in the body. Antagonists are also called inhibitors |
Antagonistic effects | Drug interactions in which the effect of a combination of two or more drugs is less than the sum of the individual effects of the same drugs given alone. 1+1=<2. It is usually caused by an antagonizing effect of one drug on another |
Bioavailability | A measure of the extent of drug absorption for a given drug and route. |
Biotransformation | One or more biochemical reactions involving a parent drug. Biotransformation occurs mainly in the Liv and produces a metabolite that is either inactive or active. |