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Stack #152471
pharm ch 16, kilgore lvl1
Question | Answer |
---|---|
stimulants | drugs that stimulate a specific area of the brain or spinal cord |
sympathomimetic drugs | CNS stimulants (like noradrenergics drugs or dopaminergic drugs) whose actions resemble or mimic those of the SNS |
-structural similarities -site of therapeutic action in CNS -Major therapeutic usuages | classifications of sympathomimetic drugs |
CNS stimulant uses | -analeptics -treatment of ADHD, narcolepsy, migraines -appitite control (anorexiants) |
AEs of CNS stimulants | symptoms typical of SNS responses (speed up body) (tachycardia, hypertension, palpitations, dry mouth, etc...) |
CNS stimulants used for ADHD | -methylphenidate (Concerta, Ritalin) -atomoxetine (strattera) |
CNS stimulants for anorexiants | -sibutramine (Meridia) -anorexiants s/b used only for short periods of time |
orlistat (Henical) | used for anorexiant, but a lipase inhibitor, NOT CNS stimulant |
Methylzanthines | caffeine, aminophylline, theophylline -used as analeptics -currently less frequent use |
Serotonin receptor agonist | new class of CNS stims use to treat migraine headaches by stimulating specific receptors in brain (5-HT1) -may be referred to as triptans |
amphetamines | - used to treat ADHD & narcolepsy - stimulate cerebral cortex and thalamus - effects similar to SNS stimulation |
caffeine | -OTC and in foods -contraindicated w/ cardiac dysrhythmias |
methylphenidate | -amphetamine used for ADHD (ritaline.concerta) |
phentermine (Ionamin) | - sympathomimetic anorexiant |
sibutramine (Meridia) | -anorexiant that inhibits reuptake of norepinephrine and serotonin which results in reduced appetite |
sumatriptan (Imitrex) | -original prototype SSRA (Seratonin agonists) |