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Stack #158878
kilgore lvl1: cholinergic agonists
Question | Answer |
---|---|
effects of cholinergic agonist on nicotinic receptors | stimulation of sympathetic and parasympathetic postganglionic nerves (mixed SNS/PSNS response) |
Effect of cholinergic agonist on mucarinic receptors on the Eye | pupil constricts (miosis) with decreased accomidation |
Effect of cholinergic agonist on mucarinic receptors on the Heart | decreased rate, and reduction of B/P |
Effect of cholinergic agonist on mucarinic receptors on the Blood vessels | vasodilation |
Effect of cholinergic agonist on mucarinic receptors on the lungs | bronchi constriction & promotion of secretions |
Effect of cholinergic agonist on mucarinic receptors on the bladder | increased bladder pressure & relaxation of sphincter to assist in voiding |
Effect of cholinergic agonist on mucarinic receptors on the GI tract | salivation, increased secretions, increased intestinal tone & motility, and aids in defecation |
Effect of cholinergic agonist on mucarinic receptors on the sweat glands | increases secretion |
What acronym helps to remember PSNS-stimulation effects? | SLUDD salivation, lacrimation, urination, digestion & defecation |
Effect of cholinergic agonist on nicotinic receptors on the bronchi | None |
Effect of cholinergic agonist on nicotinic receptors on the heart | increased heart rate & B/P |
Effect of cholinergic agonist on nicotinic receptors on the blood vessels | vasoconstriction |
Effect of cholinergic agonist on nicotinic receptors on the eye | pupil constriction and decreased accommodation |
Effect of cholinergic agonist on nicotinic receptors on the GI tract | increased tone & motility, no effect on sphinters |
Effect of cholinergic agonist on nicotinic receptors on the urinary system | increased tone & motility, relaxed urinary sphincter |
Effect of cholinergic agonist on nicotinic receptors on glandular secretions | No effect |
Effect of cholinergic agonist on nicotinic receptors on skeletal muscles | increased contraction |
Effect of cholinergic agonist on muscarinic receptors on the skeletal muscles | No effect |
key facts on bethanechol | stimulates receptors in bladder to increase tone & motility and relaxation of sphincter >used for urinary retention mgmt >can aid GI motility post-op |
key facts on physostigmine | ACE inhibitor, so raises ACh levels >used for myasthenia gravis >reverses NMBAs post-op >opthalmic uses as well |
key facts on pyridostigmine | ACE inhibitor >treat myasthenia gravis >reversal of NMBAs post-op >not used for opthalmic purposes |
key facts on donepezil | >ACE inhibitor more specific to CNS tissue >treat mild to moderate alzheimer's |
typical side-effects from cholinergic agonists | nausea, vomiting, diarrhea, sweating, bradycardia, reduced respiration |