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Neuro
NPTE
Question | Answer |
---|---|
3 elements of Glasgow Coma Scale | eye opening, motor response, verbal response |
Scoring of GCS | 3-8 severe, 9-12 moderate, 13-15 minor |
State defined by no eye opening even to pain, failure to obey commands, inability to speak | Coma |
Return of sleep/wake cycles, normalization of basic functions, lack of cognitive responsiveness | Vegetative state |
Central language DO with speech is awkward, restricted, interrupted, produced with effort | Expressive aphasia (Broca’s, nonfluent, motor) |
Expressive aphasia result of | L hemisphere – Broca’s area |
Impairment of speech production | Dysarthria |
Central language DO where spontaneous speech preserved/smooth while auditory comprehension impaired | Receptive or Wernicke’s aphasa |
Receptive aphasia is result of damage to | Posterior frist temporal gyrus of L hemisphere (Wernicke’s area) |
Severe aphasia with impairments in comprehension & production of language | Global aphasia |
Periods of apnea followed by gradually increasing depth/frequency of respirations | Cheyne Stokes respiration |
Cheyne Stokes caused by | depression of frontal lobe and diencephalic dysfunction increased ICP |
Increased rate and depth of respirations | Hyperventilation |
Abnormal respiration with prolonged inspiration | Apneustic breathing |
Signs of meningeal irritation | Kernig’s sign, Brudinski’s sign, guarding in neck flexion, photophobia, disorientation, restlessness, persistent HA that increases with head down, altered vitals, weakness |
Kernig’s sign | meningeal irritation. Supine with flexed hip/knee to chest then extend knee. |
Brudzinski’s sign | meningeal irritation. Supine, flex neck. Causes flexion of hips/knees |
Increased ICP leads to | restless, confused, decr LOC, incr BP, widening pulse P & slowed pulse, Cheyne-Stokes, elevated temp, HA, vomiting, unequal pupils, slowed PLRs, dilated pupils*, papilledema, weakness, hemiplegia, Babinski, decorticate or decerebrate rigidity, seizures |
Kinesthesia | movement sense |
Pallesthesia | vibration sense with tuning fork |
Combined cortical sensation testing | Discriminative sensory tests including Sterognosis, Tactile Localization, Two Point Discrimination, Bilateral Simultaneous Discrimination, Barognosis, Graphesthesia |
Stereognosis | ID familiar objects by touch |
Two point discrimination | ability to recognize one or two blunt points applied to skin simultaneously |
Barognosis | ability to differentiate weights |
Graphesthesia | ability to ID numbers, letters or symbols traced on skin |
Homonymous hemianopsia | loss of half of visual field in each eye contralateral to side of cerebral hemisphere lesion |
Somatognosia | body scheme disorder – unable to ID body parts or relations to each other |
Unilateral neglect | patient ignores one side of body and stimuli from that side |
Anosognosia | severe neglect or denial of severity of condition |
Form constancy | pick out object from array of similar shapes but different sizes |
Spatial relations | pt duplicates a pattern of 2-3 blocks |
Topographical disorientation | navigation of a familiar route |
Vertical disorientation | inability to accurately determine what is upright |
Agnosia | inability to recognize familiar objects with one sensory modality |
Apraxia | inability to perform voluntary learned movements in the absence of loss of sensation , strength, coordination, attention, or comprehension. Breakdown in conceptual or motor production system or both |
Ideomotor apraxia | cannot perform task on command, but can do independently |
Ideational apraxia | cannot perform the task at all, either on command or independently |
Clasp-knife response | marked resistance to PROM suddenly gives way |
Clonus | maintained stretch stimulus produces cyclical spasmodic contraction, usu plantar flexors or wrist flexors |
Babinski | DF of great toe with fanning of other toes with stroke to lateral bottom of foot |
Babinski indicates | corticospinal (pyramidal) tract disruption |
Hyperreflexia | increased DTRs |
Lead pipe Rigidity | uniform throughout range |
Cogwheel rigidity | interrupted by series of jerks |
Decerebrate posturing | increased tone in extension, seen in brainstem lesions between superior colliculus and vestibular nucleus |
Decorticate posturing | UEs in flexion, LEs in extension, seen in brainstem lesions above superior colliculus |
Opisthotonos | arching back of head back and heels with UEs rigidly flexed. Seen in severe meningitis, tetanus, epilepsy, strychnine poisoning |
Plantar reflex | Normal is PF of toes in response to stroking lateral sole of foot from calcaneus to 5th met, S1-2, tibial nerve |
Abdominal reflex | T6-L1, lateral to medial scratching of skin to umbilicus in each of 4 quadrants should cause deviation of umbilicus to stimulus |
Cremasteric reflex | L1-L2, stroking of skin on inner thigh elevates testicle, lost in SCI and Corticospinal lesions |
Extrapyramidal disorders (basal ganglia dysfunction) | Tics, Chorea, athetosis, tremors, myoclonus |
Tics | spasmodic contractions of specific muscles |
Chorea | relatively quick twitches or dancing movments |
Athetosis | slow, irregular, twisting movements, esp in UEs |
Tremor | continuous quivering mvmt, rhythmic, oscillatory observed at rest |
Myoclonus | single, quick jerk |
Cerebellar disorders cause | intention tremors |
Cortical disorders cause | seizures, tonic/clonic convulsive mvmts |
Dyssynergia | impaired ability to associate muscles together for complex mvmt |
Dysmetria | impaired ability to judge distance or range of movement |
Dysdiadochokinesia | impaired ability to perform rapid alternating movements |
Where is Broca's area located? | inferior portion of frontal lobe |
Where is Wernicke's area located? | posterior superior temporal gyrus |
What impairments are seen with frontal lobe lesions? | CL weakness (primary motor cortex), preservation, inattention, personality changes and emotional liability Brocas Area - expressive aphasia |
What impairments are seen with parietal lobe lesions? | CL sensory loss, decreased touch, vibration, temperature (primary sensory cortex) agraphia, alexia, apraxia and agnosias impaired taste |
What impairments are seen with temporal lobe lesions? | Wernicke's aphasia, aggression, decreased memory, learning and facial recognition |
What impairments are seen with occipital lobe lesions? | homongmous homonopsia, visual deficits, cortical blindness if both lobes |
What is the function of the frontal lobe | primary motor cortex, Brocas, orientation, personality and self-awareness |
what is the function of the parietal lobe | Primary sensory cortex, meaning of objects, touch, vibration, kinesthesia, temp. Spatial and visual perseption |
Spatial and visual perseption function is located in what lobe | parietal |
Which part of the brain is responsible for determining the meaning of objects | parietal |
what is the function of the temporal lobe | primary auditory cortex, wernickes area - receptive language. Memory and learning |
What are neoglisms? | word substitutions that are unrecognizable. ex: with Wernicke's |
Asterognosis | cannot recognize an object by touch |
constructional apraxia | cannot visualize how to perform a task |
2 examples of Anterior horn cell pathologies | ALS and polio |
Myasthenia gravis is what type of degeneration | degeneration of the neuromuscular junction |
anterior cord syndrome | hyper V, loss of motor (corticospinal) and pain & temp (spinothalamic) |
posterior cord syndrome | hyper / motor preserved, loss of pain, proprio, 2point discrimination and steroginosis |
central cord sndrome | hyper / Motor worse than sensory, UE worse than LE DCML, spinothalamic and corticospinal |