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Antimanics (Lithium)
Mr. D Pharmacology Final
| Term | Definition |
|---|---|
| Thioridazine | Mellaril |
| Clonazapam | Klonopin |
| Clozapine | Clozaril |
| Risperidone | Risperdal |
| Quetiapine | Seroquel |
| Antimanics are used in the treatment of | mania (mood disorders) |
| What will you see in mania? | excitement, hyperactivity, elevation of mood, very talkative (possible hallucinations) |
| What is the most commonly used drug for the treatment of mania? | Lithium |
| What is the most common mood stabilizer? | Lithium |
| State board exams always ask at least ___ question regarding Lithium. | 1 |
| Does lithium speed up or slows down neuronal activity? | Slows down brain activity. |
| Lithium is similar to | sodium |
| Sodium is required for | the conduction of nerve impulses |
| Lithium interferes with | nerve conduction |
| Lithium's interference with nerve conduction has what affect on the individual? | Calming |
| Lithium is used to treat | Mania in BP1 and BP2 |
| Sodium causes | neurotransmitters to jump the synaptic cleft |
| Lithium can become | toxic if over dose |
| Lithium increases the reuptake of | norepinephrine and dopamine |
| How long does lithium take to work? | 1 to 2 weeks |
| Therapeutic blood levels of lithium range from | 0.5 to 1.5 mEq/L |
| Maintenance dosage for Lithium | 900-1200mg |
| Lithium side effects | Mild to Moderate: Nausea, Tremors, Increased thirst, Increased urination |
| Lithium toxicity causes | heart and kidney damage |
| Lithium signs of overdose | vomiting, diarrhea, drowsiness, loss of equilibrium, ringing in ears(tinnitus), excessive thirst, excessive urination(wetting pants) |
| Lithium drug interactions with | Ibuprofen, Naproxen, Diuretics, SSRI antidressant |
| 2nd best choice for mania mood stabilization | anticonvulsants |
| Name anticonvulsants | Depakote, Gabapentin, Carbamazepine, Lamotrigine, Topiramate, Oxcarbazepine, Tiagabine |
| 3rd best choice for mania | Propranolol |
| How do anticonvulsants work? | They increase the inhibitory actions of GABA |
| Anticonvulsant side effects | dizziness, drowsiness, fatigue, nausea, tremors, rash, and weight gain |
| Anticonvulsant side effects increase or decrease with time? | side effects lessen with time |
| Should pregnant women take anticonvulsants? | no |
| Anticonvulsants can cause problems with what organ over time? | liver |
| Propranolol is a | Non-selective Beta blocker |
| Propranolol can be used for | anticipatory performance issues to calm down without sedation. Lowers blood pressure |
| Student used propranolol to pass | physical agility test |
| Propranolol only given if pulse rate is above | > 60 beats per minute |
| Propranolol only give if blood pressure is above | > 90/60 blood pressure |
| Mood stabilizers ok to give for | schizo affective disorder |
| Lithium works best when it is the primary medication because | it does not mix well with other drugs (Ibuprofen, Naproxen, Diuretics, SSRI antidressant) |
| fluoxetine (Prozac) daily dosage | 20-40 mg |
Created by:
Sanctus Verus
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